Objective To construct and preliminary verify a postoperative pulmonary rehabilitation nursing programme for children with double lung transplantation，aiming to promote early recovery and provide references for clinical nursing practice. Methods A convenience sampling approach was employed to select 25 cases pediatric patients who underwent bilateral lung transplantation at a tertiary teaching hospital in Hangzhou between January 2020 and September 2024，and they were divided into an experimental group and a control group according to the time of admission to the hospital. The experimental group received the newly developed post-transplant rehabilitation nursing program，which encompassed fluid management，mechanical ventilation，sequential oxygen therapy，pulmonary function training，exercise management，and process facilitation. In contrast，the control group received the standard post-lung transplantation rehabilitation protocol. Key outcomes，including mechanical ventilation duration，ICU stay，total hospitalization time，activity level，pulmonary function，incidence of adverse events and rehabilitation adherence，were compared between the 2 groups. Results Finally，24 cases completed the study，including 11 cases in the experimental group and 13 cases in the control group. After the intervention，the experimental group exhibited significantly shorter mechanical ventilation time compared to it in the control group （P=0.009）. Additionally，at discharge，the intervention group demonstrated higher activity levels and better rehabilitation compliance（P<0.05）. Conclusion The pulmonary rehabilitation nursing program for children with double lung transplantation is scientifically sound，safe，and feasible. The implementation of this program is beneficial for the early discontinuation of mechanical ventilation，improving postoperative mobility，and enhancing compliance with pulmonary rehabilitation.
