Objective To construct an evidence-based practice program of discharge preparation services for hip replacement patients based on the best evidence,and to evaluate its clinical effects,aiming to provide references for the implementation of relevant interventions. Methods Knowledge to Action Framework was used as a guide to summarise the best evidence on discharge preparation services for hip replacement patients and to select services based on clinical context. We selected 38 hip replacement patients and 17 healthcare professionals from the Department of Orthopaedic Surgery at a tertiary A hospital in Shanghai in September-October 2023 to conduct a baseline review, identify facilitating and hindering factors,and develop a practice protocol. We also selected 38 hip replacement patients and 17 healthcare professionals from November-December 2023 on this ward for evidence-based practice. Nurses’ rates of completion of review indicators,levels of knowledge of discharge preparation services,and discharge planning competencies were compared before and after practice. Patients’ readiness for discharge,hip function,and unplanned readmissions were also compared before and after the practice. Results After evidence-based practice,nurses’ completion rates of review indicators,knowledge of discharge preparation services,and discharge planning competencies were higher than baseline levels(P<0.05). Hip replacement patients showed a significant improvement in readiness for discharge and hip function(P<0.001). Conclusion The implementation of an evidence-based practice program of discharge preparation services improves nurses’ knowledge and skills,and also contributes to the discharge readiness and hip function of hip replacement patients.