Objective To construct and preliminarily validate a health education program for parents of preterm infants in family rooms of the neonatal intensive care unit based on the Rowntree model,aiming to provide a reference for clinical nursing practice. Methods A convenience sampling method was employed to select 98 preterm infants and their parents admitted to the family rooms between January and August 2025. The parental health education program based on the Rowntree model was implemented,encompassing 4 core components including goal setting,process design,outcome evaluation,and continuous improvement. The intervention covered 8 dimensions including basic care,feeding and nutrition,developmental support,symptom observation,first aid knowledge,safety precautions,special care,and post-discharge support. It was delivered through group lectures,bedside guidance,and online learning. Parenting competency and anxiety were compared before and after the intervention. Additionally,parental satisfaction,preterm growth indicators at 0,1,and 3 months corrected age,follow-up rates,and readmission rates within 1 and 3 months post-discharge were evaluated. Results A total of 98 participants completed the study. Post-intervention,the parenting competency scores significantly increased to 71.50(66.75,78.00) from a pre-intervention score of 38.00(31.00,49.25)(P<0.001). The anxiety score significantly decreased to 1.00(0,2.00) from 5.00(8.00,12.00)(P<0.001). The parental satisfaction rate was 100%. At 3 months corrected age,the preterm infants’ growth data all reached the P25-P50 levels of the standard curve,with a follow-up rate of 42.86%. The readmission rate within 3 months post-discharge was 3.06%. Conclusion The health education program for parents of preterm infants in family rooms of the neonatal intensive care unit was effective in improving parental caregiving competence, alleviating parental anxiety, and reducing the risk of rehospitalization in preterm infants. The program demonstrated scientific rigor, feasibility, and good acceptability among parents.