Research advances on fertility information needs and support for adolescent and young adult female cancer patients

doi:10.3761/j.issn.0254-1769.2022.14.017

Abstract

Abstract:

As the prognosis for adolescent and young adult cancer patients improves considerably,their concerns about fertility issues are increasing. This paper summarizes the fertility information needs of young female cancer patients,introduces the application of 3 ways of fertility information support （the implementation of multi-disciplinary cooperation in fertility counseling,the development of fertility knowledge manual,and the provision of fertility decision aids）. It also analyzes the reasons for the obstruction of fertility information support for cancer patients from the levels of health care providers and patients,in order to provide references for the development of cancer patients’ fertility information needs assessment tools and the construction of patient demand-oriented fertility information support program in the future.

Key words: Young Women, Cancer, Fertility, Information Needs, Nursing Care

摘要：

随着癌症早期筛查的实施和诊疗方案的不断改进,青年女性癌症患者的转归和预后发生较大改善,其对生育问题关注度日益增加。该文对青年女性癌症患者生育信息需求进行综述,介绍以实施多学科合作的生育咨询、开发生育知识手册、提供生育决策辅助工具为主的3种生育信息支持途径的应用情况,并分别从医护人员、患者层面分析阻碍癌症患者生育信息支持的原因,以期为研制癌症患者生育信息需求评估工具、构建以患者需求为导向的生育信息支持方案提供参考。

关键词: 青年女性, 癌症, 生育, 信息需求, 护理

WANG Songmei, ZHAO Yajie, HOU Yingge, XIAO Shuqing, LI Haozheng, YAN Ling. Research advances on fertility information needs and support for adolescent and young adult female cancer patients[J]. Chinese Journal of Nursing, 2022, 57(14): 1777-1782.

王松梅, 赵亚杰, 候莹鸽, 肖抒情, 李好正, 阎玲. 青年女性癌症患者生育信息需求及支持的研究进展[J]. 中华护理杂志, 2022, 57(14): 1777-1782.

References 46

[1]	Miller KD, Fidler-Benaoudia M, Keegan TH, et al. Cancer statistics for adolescents and young adults,2020[J]. CA Cancer J Clin, 2020, 70(6):443-459. DOI URL
[2]	朱飞, 路潜, 刘春蕾, 等. 癌症患者生育忧虑概念分析[J]. 医学研究与教育, 2021, 38(5):51-58.
	Zhu F, Lu Q, Liu CL, et al. Concept analysis of reproductive concerns among cancer patients[J]. Med Res Educ, 2021, 38(5):51-58.
[3]	梁晓燕, 方丛, 李晶洁, 等. 中国女性肿瘤患者生育力保护及保存专家共识[J]. 中国肿瘤临床, 2020, 47(5):217-221.
	Liang XY, Fang C, Li JJ, et al. Expert consensus on fertility protection and preservation of female cancer patients in China[J]. Chin J Clin Oncol, 2020, 47(5):217-221.
[4]	Geue K, Richter D, Schmidt R, et al. The desire for children and fertility issues among young German cancer survivors[J]. J Adolesc Health, 2014, 54(5):527-35. DOI URL
[5]	刘庆. 优化生育政策背景下的生殖健康服务[J]. 中国实用妇科与产科杂志, 2021, 37(11):1081-1083.
	Liu Q. Reproductive health services in optimizing fertility policy[J]. Chin J Pract Gynecol Obstet, 2021, 37(11):1081-1083.
[6]	Loren AW, Mangu PB, Beck LN, et al. Fertility preservation for patients with cancer: American Society of Clinical Oncology clinical practice guideline update[J]. J Clin Oncol, 2013, 31(19):2500-2510. DOI URL
[7]	Peate M, Meiser B, Friedlander M, et al. It’s now or never:fertility-related knowledge,decision-making preferences,and treatment intentions in young women with breast cancer an Australian fertility decision aid collaborative group study[J]. J Clin Oncol, 2011, 29(13):1670-1677. DOI URL
[8]	张璟, 刘东玲, 高乔乔, 等. 甲状腺癌患者信息需求的研究进展[J]. 中华护理教育, 2018, 15(9):703-707.
	Zhang J, Liu DL, Gao QQ, et al. Research progress on information needs of patients with thyroid cancer[J]. Chin J Nurs Educ, 2018, 15(9):703-707.
[9]	Benedict C, Thom B, N Friedman D, et al. Young adult female cancer survivors’ unmet information needs and reproductive concerns contribute to decisional conflict regarding posttreatment fertility preservation[J]. Cancer, 2016, 122(13):2101-2109. DOI URL
[10]	陈利群, 王文茹. 信息支持在护理中的运用研究进展[J]. 上海护理, 2001, 1(4):34-35.
	Chen LQ, Wang WR. Research progress on the application of information support in nursing[J]. Shanghai Nurs J, 2001, 1(4):34-35.
[11]	Letourneau JM, Ebbel EE, Katz PP, et al. Pretreatment fertility counseling and fertility preservation improve quality of life in reproductive age women with cancer[J]. Cancer, 2012, 118(6):1710-1717. DOI PMID
[12]	周怡, 郭映纯, 方丛. 女性儿童和青少年肿瘤患者生育力保存研究进展[J]. 生殖医学杂志, 2020, 29(1):115-119.
	Zhou Y, Guo YC, Fang C. Fertility preservation in female children and adolescents with cancer[J]. J Reproductive Med, 2020, 29(1):115-119.
[13]	Goossens J, Delbaere I, Van Lancker A, et al. Cancer patients’ and professional caregivers’ needs,preferences and factors associated with receiving and providing fertility-related information:a mixed-methods systematic review[J]. Int J Nurs Stud, 2014, 51(2):300-319. DOI PMID
[14]	Johnson AC, Mays D, Rehberg K, et al. Knowledge and beliefs about oncofertility and associations with quality of life among adolescent and young adult survivors of pediatric cancer[J]. J Adolesc Young Adult Oncol, 2018, 7(4):424-429. DOI URL
[15]	郑丹萍, 董鑫, 王晓晶. 年轻乳腺癌患者生育计划及知识与治疗决策的研究[J]. 护理学杂志, 2015, 30(22):31-34.
	Zheng DP, Dong X, Wang XJ. Fertility plan,knowledge and decision-making preferences in young breast cancer women[J]. J Nurs Sci, 2015, 30(22):31-34.
[16]	谢幸, 沈源明. 妇科恶性肿瘤生育力保护的权衡与决策[J]. 中国实用妇科与产科杂志, 2019, 35(6):609-611. DOI
	Xie X, Shen YM. Judgments in fertility-sparing surgery for gynecological malignancies[J]. Chin J Pract Gynecol Obstet, 2019, 35(6):609-611.
[17]	Carter J, Sonoda Y, Abu-Rustum NR. Reproductive concerns of women treated with radical trachelectomy for cervical cancer[J]. Gynecol Oncol, 2007, 105(1):13-16. DOI URL
[18]	Rubinsak LA, Christianson MS, Akers A, et al. Reproductive health care across the lifecourse of the female cancer patient[J]. Support Care Cancer, 2019, 27(1):23-32. DOI PMID
[19]	刘雅, 张欣文, 李静, 等. 乳腺癌辅助化疗患者更年期综合征及相关因素[J]. 中国老年学杂志, 2018, 38(2):466-468.
	Liu Y, Zhang XW, Li J, et al. Climacteric syndrome and related factors in breast cancer patients undergoing adjuvant chemotherapy[J]. Chin J Gerontol, 2018, 38(2):466-468.
[20]	Villarreal-Garza C, López-Martínez EA, Martínez-Cannon BA, et al. Medical and information needs among young women with breast cancer in Mexico[J]. Eur J Cancer Care (Engl), 2019, 28(4):e13040.
[21]	Cruickshank S, Hume A. The experience of providing support about menopausal symptoms to women with breast cancer[J]. Eur J Oncol Nurs, 2014, 18(1):110-117. DOI PMID
[22]	李敏丽, 孙慧敏, 邵雨娜, 等. 育龄期乳腺癌患者化疗相关闭经体验的现象学研究[J]. 护理学杂志, 2018, 33(12):4-7.
	Li ML, Sun HM, Shao YN, et al. A phenomenological study on child-bearing women with breast cancer:the experiences of chemotherapy-related amenorrhea[J]. J Nurs Sci, 2018, 33(12):4-7.
[23]	葛晓玲, 宋永霞, 虞苗, 等. 妇科癌症患者特异性支持照护需求的质性研究[J]. 中华现代护理杂志, 2019, 25(22):2792-2796.
	Ge XL, Song YX, Yu M, et al. A qualitative study on the specific supportive care needs of patients with gynecological cancer[J]. Chin J Mod Nurs, 2019, 25(22):2792-2796.
[24]	乔杰, 夏曦, 李红真. 生育力保护与妇科恶性肿瘤治疗后患者的辅助生育问题[J]. 实用妇产科杂志, 2014, 30(10):729-731.
	Qiao J, Xia X, Li HZ. Fertility protection and treatment of gynecological malignant tumors assisted reproductive problems in post-mortem patients[J]. J Pract Obstet Gynecol, 2014, 30(10):729-731.
[25]	Kim J, Mersereau JE, Su HI, et al. Young female cancer survivors’ use of fertility care after completing cancer treatment[J]. Support Care Cancer, 2016, 24(7):3191-3199. DOI URL
[26]	Corney RH, Swinglehurst AJ. Young childless women with breast cancer in the UK:a qualitative study of their fertility-related experiences,options,and the information given by health professionals[J]. Psychooncology, 2014, 23(1):20-26. DOI URL
[27]	李娜, 黄婉维, 张丽娟, 等. 需求理论视角下年轻乳腺癌患者生育意愿和忧虑的质性研究[J]. 中华现代护理杂志, 2021, 27(25):3390-3396.
	Li N, Huang WW, Zhang LJ, et al. Fertility intension and concern of young breast cancer patients from the perspective of need theory:a qualitative study[J]. Chin J Mod Nurs, 2021, 27(25):3390-3396.
[28]	Oktay K, Harvey BE, Partridge AH, et al. Fertility preservation in patients with cancer:ASCO clinical practice guideline update[J]. J Clin Oncol, 2018, 36(19):1994-2001. DOI URL
[29]	Lambertini M, Peccatori FA, Demeestere I, et al. Fertility pre-servation and post-treatment pregnancies in post-pubertal can-cer patients:ESMO clinical practice guidelines[J]. Ann Oncol, 2020, 31(12):1664-1678. DOI PMID
[30]	张贤贤, 张利霞, 贾智慧, 等. 夫妻自我表露在青年乳腺癌患者癌症复发恐惧干预中的应用研究[J]. 中华护理杂志, 2019, 54(11):1610-1614. DOI
	Zhang XX, Zhang LX, Jia ZH, et al. Application and effect eva-luation of marital self-disclosure intervention on the fear of cancer recurrence in young breast cancer patients[J]. Chin J Nurs, 2019, 54(11):1610-1614.
[31]	Wright CI, Coad J, Morgan S, et al. ‘Just in case’:the fertility information needs of teenagers and young adults with cancer[J]. Eur J Cancer Care (Engl), 2014, 23(2):189-198. DOI URL
[32]	马丁. 肿瘤生殖学概述[J]. 中国实用妇科与产科杂志, 2018, 34(12):1305-1308. DOI
	Ma D. Overview of tumor reproduction[J]. Chin J Pract Gynecol Obstet, 2018, 34(12):1305-1308.
[33]	Vu JV, Llarena NC, Estevez SL, et al. Oncofertility program implementation increases access to fertility preservation options and assisted reproductive procedures for breast cancer patients[J]. J Surg Oncol, 2017, 115(2):116-121. DOI URL
[34]	汪丹丹, 张苇, 郑蔚, 等. 生育咨询及教育干预对年轻妇科恶性肿瘤患者生育忧虑的影响[J]. 护理学杂志, 2020, 35(18):4-7.
	Wang DD, Zhang W, Zheng W, et al. Effect of fertility consultation and education intervention on reproductive concerns of young gynecological malignant cancer patients[J]. J Nurs Sci, 2020, 35(18):4-7.
[35]	Tam S, Puri N, Stephens D, et al. Improving access to standardized fertility preservation information for older adolescents and young adults with cancer:using a user-centered approach with young adult patients,survivors,and partners to refine fertility knowledge transfer[J]. J Cancer Educ, 2018, 33(3):528-535. DOI URL
[36]	Silva C, Almeida-Santos AT, Melo C, et al. Antineoplastic agents and(in) fertility:informing patients to improve decisions[J]. J Adolesc Young Adult Oncol, 2018, 7(3):306-314. DOI URL
[37]	Elwyn G, O’connor A, Stacey D, et al. Developing a quality criteria framework for patient decision aids:online international Delphi consensus process[J]. BMJ, 2006, 333(7565):417. DOI URL
[38]	Peate M, Meiser B, Cheah BC, et al. Making hard choices ea-sier:a prospective,multicentre study to assess the efficacy of a fertility-related decision aid in young women with early-stage breast cancer[J]. Br J Cancer, 2012, 106(6):1053-1061. DOI URL
[39]	Van Den Berg M, Van Der Meij E, Bos AME, et al. Development and testing of a tailored online fertility preservation decision aid for female cancer patients[J]. Cancer Med, 2021, 10(5):1576-1588. DOI URL
[40]	张凤春, 马越, 林玉梅, 等. 三级甲等医院肿瘤相关科室医师对于患者生育力保存认知度的调查[J]. 上海交通大学学报(医学版), 2018, 38(5):514-519.
	Zhang FC, Ma Y, Lin YM, et al. Survey on physicians who engage in cancer diagnosis and treatment from third-grade class a hospitals regarding the perceptions of cancer patients’ fertility preservation[J]. J Shanghai Jiao Tong Univ Med Sci, 2018, 38(5):514-519.
[41]	Ussher JM, Cummings J, Dryden A, et al. Talking about fertility in the context of cancer:health care professional perspectives[J]. Eur J Cancer Care(Engl), 2016, 25(1):99-111.
[42]	Zhang HF, Jiang QH, Fang YH, et al. Perceptions of oncology nurses regarding fertility preservation and providing oncofertility services for men of childbearing age with cancer[J]. J Cancer Educ, 2021:127-131.
[43]	Ussher JM, Parton C, Perz J. Need for information,honesty and respect:patient perspectives on health care professionals communication about cancer and fertility[J]. Reprod Health, 2018, 15(1):2. DOI PMID
[44]	杨孟叶, 张艳, 钮芳芳. 辅助生殖技术助孕患者健康信息需求及干预的研究进展[J]. 中华护理杂志, 2021, 56(1):143-148. DOI
	Yang MY, Zhang Y, Niu FF. Research progress on health information needs and interventions for patients receiving assisted reproductive technology for pregnancy[J]. Chin J Nurs, 2021, 56(1):143-148.
[45]	孙倩, 王璐, 郑树基, 等. 数字化健康干预在青年癌症患者心理康复中的应用进展[J]. 中华护理杂志, 2019, 54(2):301-306. DOI
	Sun Q, Wang L, Zheng SJ, et al. Application progress on digital health intervention of psychological rehabilitation in adolescent and young adult cancer survivors[J]. Chin J Nurs, 2019, 54(2):301-306.
[46]	Benedict C, Hahn AL, Mccready A, et al. Toward a theoretical understanding of young female cancer survivors’ decision-making about family-building post-treatment[J]. Support Care Cancer, 2020, 28(10):4857-4867. DOI URL