白血病患儿症状群评估工具的研究进展

doi:10.3761/j.issn.0254-1769.2021.08.023

摘要/Abstract

摘要：

白血病为儿童时期发病率最高的恶性肿瘤,评估症状群可以理解患儿经历的症状,有助于症状的联合管理。该文综述了国内外白血病患儿症状群评估工具的内容、特点及应用情况。建议根据现有普适性工具的特点并结合白血病患儿疾病特点,开发适合白血病患儿症状群的特异性评估工具,为通过有效管理提升患儿生活质量提供依据。

关键词: 白血病, 症状群, 评估工具, 综述, 儿科护理学

Abstract:

Leukemia is the malignant tumor with the highest incidence in childhood. Assessing the symptom group can help to understand the symptoms experienced by children from a broader perspective,which is useful for the joint management of symptoms. This article reviews the content,characteristics and application of symptom cluster assessment tools for children with leukemia at home and abroad. It is recommended to develop specific assessment tools suitable for the identification of symptom clusters in children with leukemia based on the characteristics of existing universal tools and the disease characteristics of children with leukemia,so as to provide references for effective management to improve the quality of life of children.

Key words: Leukemia, Symptom Cluster, Assessment Tool, Review, Pediatric Nursing

顾嘉鑫,王泠,刘晓黎,颜霞. 白血病患儿症状群评估工具的研究进展[J]. 中华护理杂志, 2021, 56(8): 1261-1266.

GU Jiaxin,WANG Ling,LIU Xiaoli,YAN Xia. Progress in the research of symptom clusters assessment tools in children with leukemia[J]. Chinese Journal of Nursing, 2021, 56(8): 1261-1266.

图/表 1

参考文献 42

[1]	周平, 熊昊, 李建新, 等. 初诊儿童急性淋巴细胞白血病治疗相关死亡的危险因素的分析[J]. 中国实验血液学杂志, 2020, 28(6):1837-1841.
	Zhou P, Xiong H, Li JX, et al. Effect of the risk factors for treatment-related death in children with acute lymphoblastic leukemia[J]. J Exp Hematol, 2020, 28(6):1837-1841.
[2]	王春立, 吴心怡, 王旭梅, 等. 白血病患儿鞘内注射后去枕平卧时间对并发症的影响研究[J]. 中华护理杂志, 2019, 54(1):25-30.
	Wang CL, Wu XY, Wang XM, et al. Study on the effect of occiput-free and supine time after intrathecal injection in children with leukemia on complications[J]. Chin J Nurs, 2019, 54(1):25-30.
[3]	Zheng R, Peng X, Zeng H, et al. Incidence,mortality and survival of childhood cancer in China during 2000-2010 period:a population-based study[J]. Cancer Lett, 2015, 363(2):176-180. DOI URL
[4]	Tasian SK, Loh ML, Hunger SP. Childhood acute lymphoblastic leukemia:integrating genomics into therapy[J]. Cancer, 2015, 121(20):3577-3590. DOI PMID
[5]	郑渊, 刘可, 卜秀青, 等. 急性白血病患儿化疗期间症状群的调查分析[J]. 中华护理杂志, 2016, 51(11):1320-1324.
	Zheng Y, Liu K, Bu XQ, et al. Survey and analysis of symptom clusters in children with acute leukemia during chemotherapy[J]. Chin J Nurs, 2016, 51(11):1320-1324.
[6]	唐慧, 杨艳, 李映兰, 等. 儿童早期预警评分在急性淋巴细胞白血病患儿中的应用[J]. 中华护理杂志, 2017, 52(12):1422-1426.
	Tang H, Yang Y, Li YL, et al. Application of Early Warning Score in Children with acute lymphoblastic leukemia[J]. Chin J Nurs, 2017, 52(12):1422-1426.
[7]	Dodd MJ, Miaskowski C, Paul SM. Symptom clusters and their effect on the functional status of patients with cancer[J]. Oncol Nurs Forum, 2001, 28(3):465-470. PMID
[8]	Kim HJ, McGuire DB, Tulman L, et al. Symptom clusters:concept analysis and clinical implications for cancer nursing[J]. Cancer Nurs, 2005, 28(4):270-284.
[9]	Miaskowski C, Barsevick A, Berger A, et al. Advancing symptom science through symptom cluster research：expert panel proceedings and recommendations[J]. J Natl Cancer Inst, 2017, 109(4)：djw253.
[10]	Collins JJ, Byrnes ME, Dunkel IJ, et al. The measurement of symptoms in children with cancer[J]. J Pain Symptom Manag, 2000, 19(5):363-377. PMID
[11]	Yeh CH, Chiang YC, Chien LC, et al. Symptom clustering in older Taiwanese children with cancer[J]. Oncol Nurs Forum, 2008, 35(2):273-281. DOI URL
[12]	Plenert E, Grimes A, Sugalski A, et al. Translating the Symptom Screening in Paediatrics Tool(SSPedi) into North American Spanish and among Spanish-speaking children receiving cancer treatments:evaluating understandability and cultural relevance in a multiple-phase descriptive study[J]. BMJ Open, 2020, 10(11):e037406. DOI URL
[13]	李蓉蓉, 马金玲, 阐玉英, 等. 急性淋巴细胞白血病患儿化疗期间症状群的纵向研究[J]. 护理学杂志, 2019, 34(16):5-9.
	Li RR, Ma JL, Chan YY, et al. Symptom clusters among children with acute lymphocytic leukemia during chemotherapy:a longitudinal study[J]. J Nurs Sci, 2019, 34(16):5-9.
[14]	Portenoy RK, Thaler HT, Kornblith AB, et al. The Memorial Symptom Assessment Scale:an instrument for the evaluation of symptom prevalence,characteristics and distress[J]. Eur J Cancer, 1994, 30A(9):1326-1336. PMID
[15]	冯芳茗, 楼建华, 徐红, 等. 癌症患儿症状体验的现况调查[J]. 中国护理管理, 2012, 12(1):30-34.
	Feng FM, Lou JH, Xu H, et al. Symptom experience among children with cancer:a cross-sectional study[J]. Chin Nurs Manag, 2012, 12(1):30-34.
[16]	Rodgers C, Highberger M, Powers K, et al. Symptom trajectories of adolescents during hematopoietic stem cell recovery[J]. Cancer Nurs, 2019, 42(6):468-474. DOI PMID
[17]	Yeh CH, Wang CH, Chiang YC, et al. Assessment of symptoms reported by 10 to 18-year-old cancer patients in Taiwan[J]. J Pain Symptom Manage, 2009, 38(5):738-746. DOI URL
[18]	Pöder U, Ljungman G, von Essen L. Parents’ perceptions of their children’s cancer-related symptoms during treatment:a prospective,longitudinal study[J]. J Pain Symptom Manage, 2010, 40(5):661-670. DOI URL
[19]	Alhelih E, Ghazi Baker O, Aboshaiqah AE. Retracted:symptom trajectories and occurrence in older Saudi children with cancer during a course of chemotherapy[J]. Eur J Cancer Care(Engl), 2017, 26(4):e12555.
[20]	Collins JJ, Devine TD, Dick GS, et al. The measurement of symptoms in young children with cancer:the validation of the Memorial Symptom Assessment Scale in children aged 7-12[J]. J Pain Symptom Manage, 2002, 23(1):10-16. DOI URL
[21]	Williams PD, Williams AR, Kelly KP, et al. A symptom checklist for children with cancer:the Therapy-Related Symptom Checklist-Children[J]. Cancer Nurs, 2012, 35(2):89-98. DOI PMID
[22]	Olagunju AT, Sarimiye FO, Olagunju TO, et al. Child’s symptom burden and depressive symptoms among caregivers of children with cancers:an argument for early integration of pediatric palliative care[J]. Ann Palliat Med, 2016, 5(3):157-165. DOI PMID
[23]	Linder LA, Al-Qaaydeh S, Donaldson G. Symptom characteristics among hospitalized children and adolescents with cancer[J]. Cancer Nurs, 2018, 41(1):23-32. DOI PMID
[24]	Abu-Saad Huijer H, Sagherian K, Tamim H. Quality of life and symptom prevalence as reported by children with cancer in Lebanon[J]. Eur J Oncol Nurs, 2013, 17(6):704-710. DOI PMID
[25]	Baggott C, Baird J, Hinds P, et al. Evaluation of Sisom:a computer-based animated tool to elicit symptoms and psychosocial concerns from children with cancer[J]. Eur J Oncol Nurs, 2015, 19(4):359-369. DOI URL
[26]	Williams PD, Schmideskamp J, Ridder EL, et al. Symptom monitoring and dependent care during cancer treatment in children:pilot study[J]. Cancer Nurs, 2006, 29(3):188-197. PMID
[27]	Williams PD, Piamjariyakul U, Shanberg R, et al. Monitoring and alleviation of symptom occurrence and severity among Thai children and adolescents during cancer treatments[J]. J Pediatr Oncol Nurs, 2015, 32(6):417-428. DOI PMID
[28]	Williams PD, Robinson J, Williams AR. Symptom occurrence and severity on the therapy-related symptom checklist for children among Hispanic pediatric oncology outpatients[J]. Cancer Nurs, 2014, 37(3):E12-E20.
[29]	Mansouri A, Motaghedi R, Rashidian A, et al. Validity and reliability assessment of the Persian version of therapy-related symptom checklist[J]. Iran J Med Sci, 2017, 42(3):292-300.
[30]	Xia W, Li HCW, Lam KWK, et al. The impact of hematologic cancer and its treatment on physical activity level and quality of life among children in mainland China:a descriptive study[J]. Cancer Nurs, 2019, 42(6):492-500. DOI URL
[31]	Tomlinson D, Dupuis LL, Gibson P, et al. Initial development of the symptom screening in pediatrics tool(SSPedi)[J]. Support Care Cancer, 2014, 22(1):71-75. DOI PMID
[32]	O’Sullivan C, Dupuis LL, Gibson P, et al. Refinement of the symptom screening in pediatrics tool(SSPedi)[J]. Br J Cancer, 2014, 111(7):1262-1268. DOI URL
[33]	Hyslop S, Dupuis LL, Baggott C, et al. Validation of the proxy version of symptom screening in pediatrics tool in children receiving cancer treatments[J]. J Pain Symptom Manage, 2018, 56(1):107-112. DOI URL
[34]	Cadamuro SA, Franco JO, Paiva CE, et al. Symptom screening in paediatrics tool for screening multiple symptoms in Brazilian patients with cancer:a cross-sectional validation study[J]. BMJ Open, 2019, 9(8):e028149. DOI URL
[35]	Larouche V, Revon-Rivière G, Johnston D, et al. Translating the Symptom Screening in Pediatrics Tool(SSPedi) into French and among French-speaking children receiving cancer treatments,evaluating understandability and cultural relevance in a multiple-phase descriptive study[J]. BMJ Open, 2020, 10(4):e035265. DOI URL
[36]	Johnston DL, Hyslop S, Tomlinson D, et al. Describing symptoms using the Symptom Screening in Pediatrics Tool in hospitalized children with cancer and hematopoietic stem cell transplant recipients[J]. Cancer Med, 2018, 7(5):1750-1755. DOI URL
[37]	Tomlinson D, Hyslop S, Stein E, et al. Development of mini-SSPedi for children 4-7 years of age receiving cancer treatments[J]. BMC Cancer, 2019, 19(1):32. DOI PMID
[38]	Loves R, Plenert E, Tomlinson V, et al. Changes in taste among pediatric patients with cancer and hematopoietic stem cell transplantation recipients[J]. Qual Life Res, 2019, 28(11):2941-2949. DOI URL
[39]	刘砚燕. 儿童自我报告结局测量信息系统在儿童癌症人群中的测评[D]. 上海:第二军医大学, 2013.
	Liu YY. Measurement examination of Chinese version of pediatric PROMIS measures among children and adolescents with cancer[D]. Shanghai:Second Military Medical University, 2013.
[40]	Irwin DE, Stucky BD, Thissen D, et al. Sampling plan and patient characteristics of the PROMIS pediatrics large-scale survey[J]. Qual Life Res, 2010, 19(4):585-594. DOI URL
[41]	郭倩, 李丽, 侯黎莉. 口腔癌病人报告结局测评工具的研究进展[J]. 护理研究, 2019, 33(24):4261-4266.
	Guo Q, Li L, Hou LL. Research progress on assessment tools for mouth neoplasms patient-reported outcome[J]. Chin Nurs Res, 2019, 33(24):4261-4266.
[42]	徐艳华, 沈南平, 袁长蓉, 等. 潜类别模型用于白血病患儿多症状特征分类研究[J]. 护理学杂志, 2018, 33(19):22-25.
	Xu YH, Shen NP, Yuan CR, et al. Identifying typologies of symptoms in children with leukemia employing latent class analysis[J]. J Nurs Sci, 2018, 33(19):22-25.