Objective To develop an expert consensus on the removal of central venous access devices(hereinafter referred to as the “consensus”) to standardize related clinical practices. Methods A systematic literature search,literature quality evaluation,and synthesis were conducted. Combined with practical experience,an initial draft of the “consensus” was developed. From May to July 2025,the draft underwent revision and refinement through 2 rounds of expert Delphi surveys and 2 expert panel meetings,culminating in the final version. Results A total of 24 experts from 14 provinces/municipalities(Guangdong,Guangxi,Fujian,et al) participated in 2 rounds of Delphi survey,with response rates of 92.31% and 100%. In both Delphi rounds,expert authority coefficients were 0.903 and 0.908,respectively;mean importance scores ranged from 4.04~5.00(round 1) and 3.97~4.90(round 2);coefficients of variation were 0~0.23(round 1) and 0.06~0.25(round 2);Kendall’s W coefficients were 0.202 and 0.138(both P<0.001). This “consensus” covers the scope of application,definitions of key terms,indications for catheter removal,operational precautions,and related emergency management measures. Conclusion The “consensus” is scientific and rigorous,providing practical guidance for the procedures related to the removal of central venous access devices.