Abstract:

This report summarizes the nursing experience of an adolescent patient with Graves’ disease complicated by drug hypersensitivity syndrome. Key nursing interventions included：prompt discontinuation of the causative drug and careful administration of immunosuppressive therapy；early identification of thyroid crisis using the Burch-Wartofsky scoring system，with immediate resuscitation initiated upon detection of abnormalities；conducting dynamic temperature monitoring and employing multiple combined cooling strategies；protecting skin and mucosal barrier function while actively preventing and controlling infections；implementing family-centered health education to enhance patients’ self-efficacy and psychological resilience. Following active treatment and meticulous care，the patient’s condition improved and they were discharged after 36 days of hospitalization. During the subsequent 3-month follow-up period，no immune-related sequelae associated with drug hypersensitivity syndrome occurred.

Key words: Graves’ Disease, Drug-Induced Hypersensitivity Syndrome, Adolescent, Nursing Care

摘要：

总结1例弥漫性毒性甲状腺肿合并超敏反应综合征青少年患者的护理经验。护理要点：停止使用致敏药物，实施抗免疫药物精细管理；基于伯奇-沃托斯基点评分量表早期识别甲状腺危象，出现异常情况立即配合抢救；进行动态体温监测，采取多种策略联合降温；保护皮肤黏膜屏障功能，积极防控感染；实施以家庭为中心的健康教育，增强患者自我效能感与心理韧性。经过积极的治疗与精细化护理，患者于住院36 d后病情好转出院。出院后随访3个月，未发生药物超敏反应综合征相关免疫性后遗症。

关键词: 弥漫性毒性甲状腺肿, 药物超敏反应综合征, 青少年, 护理