Abstract:

Objective To investigate the current situation of frailty in patients with home peritoneal dialysis and analyze its influencing factors，so as to provide bases for early identification of high-risk groups and targeted clinical intervention. Methods From October to December 2024，205 home-based peritoneal dialysis patients under long-term follow-up at a tertiary A hospital in Zhongshan，Guangdong Province，were selected by convenience sampling. The General Information Questionnaire，Fried Phenotype Scale，Nutritional Risk Screening Tool，Exercise Self-Efficacy Scale，and Social Support Rating Scale were used to investigate the influencing factors of frailty in home-based peritoneal dialysis patients by ordinal logistic regression analysis. Results A total of 201 valid questionnaires were collected. The prevalence of frailty among home-based peritoneal dialysis patients was 24.3%，while 39.3% were in the pre-frailty stage，and 36.3% showed no frailty. Ordinal logistic regression analysis revealed that age，residence location，primary disease，sleep status，serum albumin concentration，and exercise self-efficacy level were influencing factors of frailty in the home peritoneal dialysis patients（P<0.05）. Conclusion The incidence of frailty in patients with home peritoneal dialysis is higher，and patients with advanced age，living in rural areas，other types of primary diseases，insomnia，low serum albumin concentration and low exercise self-efficacy are more likely to develop frailty. Specialist doctors and nurses of peritoneal dialysis should pay attention to the early screening of frailty in patients with peritoneal dialysis at home，and take personalized intervention measures to prevent or delay the occurrence of frailty according to the relevant risk factors.

Key words: Home Peritoneal Dialysis, Frailty, Root Cause Analysis, Nursing Care

摘要：

目的 调查居家腹膜透析患者衰弱现状并分析其影响因素，为早期识别高危人群并开展针对性临床干预提供依据。方法 采用便利抽样法，于2024年10月—12月选取广东省中山市某三级甲等医院长期随访的205例居家腹膜透析患者作为调查对象，应用一般资料调查表、Fried衰弱表型量表、营养风险筛查表、运动自我效能量表、社会支持评定量表进行调查，采用有序多分类Logistic回归分析居家腹膜透析患者衰弱的影响因素。结果 201例居家腹膜透析患者衰弱的发生率为24.3%，衰弱前期的发生率为39.3%，36.3%的患者为无衰弱。有序多分类Logistic回归分析显示，年龄、居住地、原发疾病、睡眠状况、血清白蛋白浓度、运动自我效能水平是居家腹膜透析患者衰弱的影响因素（P<0.05）。结论 居家腹膜透析患者衰弱发生率较高，年龄大、居住地为农村、原发疾病为其他类型、失眠、血清白蛋白浓度低、运动自我效能水平低的患者更易发生衰弱。腹膜透析专科医护人员应重视对此类患者衰弱的早期筛查，针对相关危险因素采取个性化干预措施以预防或延缓衰弱发生。

关键词: 居家腹膜透析, 衰弱, 影响因素分析, 护理