Perioperative nursing care for 57 infants undergoing ABO-incompatible living donor liver transplantation

doi:10.3761/j.issn.0254-1769.2026.10.014

Chinese Journal of Nursing ›› 2026, Vol. 61 ›› Issue (10): 1402-1406.DOI: 10.3761/j.issn.0254-1769.2026.10.014

• Rare Disease and Critical Care • Previous Articles Next Articles

Perioperative nursing care for 57 infants undergoing ABO-incompatible living donor liver transplantation

WANG Fang¹(), LU Fangyan²(), WANG Yan¹, JIANG Shuying¹, TANG Saxiao³

¹ Liver Transplantation Center， the First Affiliated Hospital of Zhejiang University School of Medicine， Hangzhou 310003， China
² Nursing Department， the First Affiliated Hospital of Zhejiang University School of Medicine， Hangzhou 310003， China
³ Liver Transplantation Documentation Room， the First Affiliated Hospital of Zhejiang University School of Medicine， Hangzhou 310003， China.

Received:2025-05-27 Online:2026-05-20 Published:2026-05-09
* Corresponding author: LU Fangyan，E-mail：2196032@zju.edu.cn
Funding program:
Zhejiang Provincial Medical and Health Science and Technology Plan(2023KY105)

57例婴幼儿行ABO血型不相容亲体肝移植的围手术期护理

王芳¹(), 卢芳燕²(), 王燕¹, 蒋树英¹, 汤洒潇³

¹ 浙江大学医学院附属第一医院肝移植中心杭州市 310003
² 浙江大学医学院附属第一医院护理部杭州市 310003
³ 浙江大学医学院附属第一医院肝移植资料室杭州市 310003

通讯作者: 卢芳燕，E-mail：2196032@zju.edu.cn
作者简介:王芳：女，本科，主管护师，E-mail：787993514@qq.com
第一联系人：作者贡献声明
王芳：资料收集及分析、论文撰写；卢芳燕：选题设计、论文审阅及修改；王燕：研究指导、论文修改；蒋树英：文献检索、论文修改；汤洒潇：资料收集
基金资助:
浙江省医药卫生科技计划(2023KY105)

Abstract

Abstract:

This article summarizes the perioperative nursing experience of 57 infants undergoing ABO-incompatible living donor liver transplantation. The key points of nursing include：preoperative induction of desensitization to reduce blood group antibody titer and implement predictive nursing；early nutritional assessment and individualized nutritional care；precise administration of immunosuppressants after surgery to prevent rejection and infection；sequential anticoagulant therapy to balance the risks of embolism and bleeding；empowering parents of the children and implementing a three-level linkage of family-hospital-society care；promoting the recovery of the children and implementing phased continuous care. Through careful treatment and nursing care，all children successfully completed the surgery. A child died of hemorrhagic shock postoperatively，while the remaining 56 children recovered and were discharged. Follow-up visits ranging from 4 months to 2 years showed good recovery.

Key words: Liver Transplantation, Pediatric Nursing, Blood Type Incompatibility, Perioperative Nursing

摘要：

总结57例婴幼儿行ABO血型不相容亲体肝移植的围手术期护理经验，护理要点如下。术前诱导脱敏，降低血型抗体滴度，实施预见性护理；早期营养评估，进行个体化营养护理。术后精准服用免疫抑制剂，预防排异与感染；贯序抗凝治疗，平衡栓塞与出血风险；赋能患儿家长，实施家庭-医院-社会三级联动护理；促进患儿康复，实施分阶段延续性护理。经过精心的治疗与护理，所有患儿均顺利完成手术，术后1例患儿因出血性休克死亡，其余56例均康复出院，随访4个月至2年，恢复良好。

关键词: 肝移植, 儿科护理学, 血型不相容, 围术期护理

WANG Fang, LU Fangyan, WANG Yan, JIANG Shuying, TANG Saxiao. Perioperative nursing care for 57 infants undergoing ABO-incompatible living donor liver transplantation[J]. Chinese Journal of Nursing, 2026, 61(10): 1402-1406.

王芳, 卢芳燕, 王燕, 蒋树英, 汤洒潇. 57例婴幼儿行ABO血型不相容亲体肝移植的围手术期护理[J]. 中华护理杂志, 2026, 61(10): 1402-1406.

References 15

[1]	沈子颜, 王艳, 唐诗, 等. 肝移植儿童照护者疾病进展担忧现状及影响因素分析[J]. 中国护理管理, 2024, 24(11):1641-1645.
	Shen ZY, Wang Y, Tang S, et al. Fear of progression of care-givers of children receiving liver transplantation and its influ-encing factors[J]. Chin Nurs Manag, 2024, 24(11):1641-1645.
[2]	李全升, 王凯, 高伟. ABO血型不相容的儿童肝移植研究现状[J]. 实用器官移植电子杂志, 2024, 12(5):452-457.
	Li QS, Wang K, Gao W. Current research status of liver transplantation in children with ABO blood type incompatibi-lity[J]. Pract J Organ Transplant Electron Version, 2024, 12(5):452-457.
[3]	刘辉, 苏洵, 李万富, 等. ABO血型不相容儿童活体肝移植的临床疗效分析[J]. 实用器官移植电子杂志, 2024, 12(5):405-409.
	Liu H, Su X, Li WF, et al. Clinical efficacy analysis of living donor liver transplantation in children with ABO-incompatibi-lity[J]. Pract J Organ Transplant Electron Version, 2024, 12(5):405-409.
[4]	邓瑞桦, 李彦昀, 吕楠, 等. ABO血型不相容肝移植采用供者血型血浆置换1例[J]. 中国现代医药杂志, 2025, 27(2):94-97. DOI
	Deng RH, Li YY, Lü N, et al. A case of ABO incompatible liver transplantation with donor blood plasma exchange[J]. Mod Med J China, 2025, 27(2):94-97.
[5]	沈丹军, 盛美君, 郑虹, 等. 胆道闭锁合并肺部感染患儿行血型不相容肝移植的护理[J]. 中华急危重症护理杂志, 2025, 6(6):710-713. DOI
	Shen DJ, Sheng MJ, Zheng H, et al. Nursing care of a child with biliary atresia complicated with pulmonary infection undergoing blood group incompatible liver transplantation[J]. Chin J Emerg Crit Care Nurs, 2025, 6(6):710-713.
[6]	俞浩, 王卫利, 张微, 等. 儿童ABO血型不相容肝移植围手术期处理的研究进展[J]. 中华外科杂志, 2023, 61(2):173-176.
	Yu H, Wang WL, Zhang W. Progress in perioperative mana-gement of ABO-incompatible pediatric liver transplantation[J]. Chin J Surg, 2023, 61(2):173-176. DOI PMID
[7]	Yang MF, Wei XY, Khan AR, et al. Stratified analysis of sur-vival benefit for ABO-incompatible deceased-donor liver trans-plantation:multicenter propensity score-matched study[J]. J Clin Transl Hepatol, 2023, 11(4):827-838.
[8]	韩环立, 戴小科, 李英存, 等. ABO血型不相容儿童活体肝移植临床分析[J]. 四川大学学报(医学版), 2022, 53(5):777-781.
	Han HL, Dai XK, Li YC, et al. Clinical analysis of ABO-incompatible living-donor liver transplantation in children[J]. J Sichuan Univ Med Sci, 2022, 53(5):777-781.
[9]	中国研究型医院学会加速康复外科专业委员会. 儿童肝移植围手术期管理专家共识[J]. 中华外科杂志, 2021, 59(3):179-191.
	Enhanced Recovery After Surgery Committee of Chinese Re-search Hospital Association. Expert consensus of perioperative management in pediatric liver transplantation[J]. Chin J Surg, 2021, 59(3):179-191.
[10]	何雪瑜, 曾小芳. 1例利妥昔单抗治疗重症天疱疮患者并发皮下血肿的护理[J]. 中华护理杂志, 2021, 56(6):917-920. DOI
	He XY, Zeng XF. Nursing care of a severe pemphigus com-plicated patient with subcutaneous hematoma treated with Rituximab[J]. Chin J Nurs, 2021, 56(6):917-920.
[11]	杨静, 王华芬, 卢芳燕, 等. 肝移植患儿术后营养状况变化的影响因素分析及护理启示[J]. 中华护理杂志, 2025, 60(9):1113-1119. DOI
	Yang J, Wang HF, Lu FY, et al. Analysis of influencing factors of nutritional status changes in pediatric liver transplant patients and nursing revelation[J]. Chin J Nurs, 2025, 60(9):1113-1119.
[12]	丁维燕, 张婉莹, 董丽, 等. 肝移植术后患儿早期肠内营养支持的最佳证据总结[J]. 护理与康复, 2024, 23(12):26-31.
	Ding WY, Zhang WY, Dong L, et al. Early enteral nutrition support in pediatric liver transplant recipients:a best eviden-ce summary[J]. J Nurs Rehabil, 2024, 23(12):26-31.
[13]	崔向丽, 沈素, 孙丽莹, 等. 儿童肝移植围手术期营养风险评估及营养支持要点[J]. 中华器官移植杂志, 2021, 42(9):566-569.
	Cui XL, Shen S, Sun LY, et al. Nutritional risk assessment and key points of nutritional support during perioperative pe-riod of liver transplantation in children[J]. Chin J Organ Tran-splant, 2021, 42(9):566-569.
[14]	中华医学会器官移植学分会, 中国医师协会器官移植医师分会, 上海医药行业协会. 中国肝、肾移植受者霉酚酸类药物应用专家共识(2023版)[J]. 中华器官移植杂志, 2023, 44(10):577-595.
	Branch of Organ Transplant of Chinese Medical Association. Branch of Organ Transplant Physicians of Chinese Medical Doctor Association. Shanghai Pharmaceutical Profession Associa-tion. Expert consensus on the use of mycophenolic acid in Chinese liver and kidney transplant recipients(2023 edition)[J]. Chin J Organ Transplant, 2023, 44(10):577-595.
[15]	王芳, 卢芳燕, 王燕. 6例经典型枫糖尿病患儿行肝移植的术后护理[J]. 中华护理杂志, 2022, 57(1):79-82. DOI
	Wang F, Lu FY, Wang Y. Postoperative nursing care of 6 children with classic maple syrup urine disease undergoing liver transplantation[J]. Chin J Nurs, 2022, 57(1):79-82. DOI

Perioperative nursing care for 57 infants undergoing ABO-incompatible living donor liver transplantation

57例婴幼儿行ABO血型不相容亲体肝移植的围手术期护理

RichHTML

PDF

Knowledge

Abstract

Cite this article

share this article

References 15

Related Articles 15

Recommended Articles

Metrics

[1]	ZHOU Xia, MA Yanyan, SHI Zhengkun, YU Haixia, ZHOU Yan, HU Hongling, LI You, CHEN Sisi, ZHANG Jinghui. A study on the application of tunneled femoral PICC in pediatric patients with difficult venous access [J]. Chinese Journal of Nursing, 2026, 61(9): 1163-1170.
[2]	LI Jia, ZHANG Yuling, XING Le, ZHANG Lifeng, NIU Xiufeng, XU Li. Construction and validation of a risk prediction model for secondary peripherally inserted central catheter tip malposition in the upper extremity of preterm infants [J]. Chinese Journal of Nursing, 2026, 61(9): 1180-1186.
[3]	ZHENG Yulin, LIU Jinning, ZHANG Jing, GUO Huimin, GU Yanmei, ZHANG Lili. Analysis of relapse to alcohol drinking and its influencing factors in patients with alcoholic liver disease after liver transplantation [J]. Chinese Journal of Nursing, 2026, 61(9): 1208-1214.
[4]	SHU Shi, ZHU Shan, YU Genzhen, ZHANG Ping, ZHOU Chenxi, PENG Wei, WANG Zhen. A qualitative study of children’s lived experiences and needs in idiopathic central precocious puberty [J]. Chinese Journal of Nursing, 2026, 61(8): 1074-1079.
[5]	LIU Suling, JIANG Weihong, LI Xiaoyan, TANG Xiaomin. Rehabilitation nursing care for a child with complete Shone’s syndrome and severe pulmonary hypertension [J]. Chinese Journal of Nursing, 2026, 61(8): 1107-1111.
[6]	FAN Na, ZHANG Xuan, DU Huajuan, HU Jiaqing, YANG Yanfei. Construction and application of gamification therapy for children with congenital heart disease surgery [J]. Chinese Journal of Nursing, 2026, 61(7): 909-916.
[7]	FENG Linjia, HAN Xiaoyun, ZHANG Chenghuan, ZHANG Qingqing. Construction and preliminary application of an intraoperative hypothermia prevention management program during cesarean section [J]. Chinese Journal of Nursing, 2026, 61(7): 917-923.
[8]	GUAN Yinghui, Yinghui Jianhui, OUYANG Yaqi, XU Le, TIAN Jiaqi, Jiaqi Qiong. Healthcare transitional experience of adolescents with type 1 diabetes to adult care：a meta-synthesis [J]. Chinese Journal of Nursing, 2026, 61(7): 979-985.
[9]	LU Mengxin, YU Xiaoyan, ZHANG Shenglong, MA Lu, WANG Ziyu, DING Jinping, XIN Tingting, ZHANG Bing-liang. A longitudinal qualitative study on the rehabilitation needs of liver transplant patients at different stages [J]. Chinese Journal of Nursing, 2026, 61(5): 660-666.
[10]	ZHOU Min, WANG Linjuan, HUANG Quelan, FU Qin, LI Jiajia, FU Kunhui, DONG Qi, MENG Lingyu. A survey of the current knowledge，attitudes，and practices of peripheral arterial catheter management among ICU nurses in 15 tertiary pediatric hospitals [J]. Chinese Journal of Nursing, 2026, 61(5): 682-688.
[11]	HUANG Jingwen, YE Guilian, YANG Hong, ZHONG Meihua, ZHOU Huaqing. Early rehabilitation nursing for a pediatric patient undergoing combined heart-lung transplantation with non-intubated spontaneous ventilation anesthesia：a case report [J]. Chinese Journal of Nursing, 2026, 61(5): 697-701.
[12]	LU Lu, ZHU Lin, ZHOU Xiao, LI Zhe, LU Fangyan. Perioperative nursing care of a patient undergoing biventricular assist device implantation surgery [J]. Chinese Journal of Nursing, 2026, 61(5): 702-706.
[13]	HE Xiaoqiong, LIU Yi, LE Li, LIU Yu. Design and application of a rapid gamified exercise board for enhancing recovery for pediatric patients undergoing laparoscopic appendectomy [J]. Chinese Journal of Nursing, 2026, 61(4): 483-489.
[14]	LIU Yancui, LIU Yu, SHEN Qin, YU Li. Influencing factors of early activity in critically ill children from the perspective of medical staff：a qualitative study [J]. Chinese Journal of Nursing, 2026, 61(4): 536-542.
[15]	ZHOU Yiwen, YU Zhuowen, XU Xiaofeng, HUANG Yuyan. Nutritional management during umbilical cord blood stem cell transplantation in a child with very early-onset inflammatory bowel disease [J]. Chinese Journal of Nursing, 2026, 61(4): 561-565.