Abstract:

Objective To explore the experience of related donors in the process of allogeneic Hematopoietic Stem Cell Transplantation（HSCT）,so as to take precision nursing and to guide clinical practice. Methods A purposive sampling and a semi-structured interview method were used in our center. 2 trained nurses interviewed the related donors of allogeneic HSCT. The content of interviews was recorded by a voice recorder. When the information was saturated,the interview was terminated. In this study,18 related donors were included. Finally,the data was analyzed by 7 steps of Colaizzi of phenomenology. Results The interview contents were summarized into 5 themes,namely the diversity of determinants of donation,physical and mental stress of donors,the heavy burden of responsibility,the feeling of neglect,the positive impact of donation. Conclusion In the process of donation,related donors suffered from pressure of physiology,psychology,life and so on. Medical staff should strengthen the communication with donors and provide more comprehensive professional guidance,so as to create a positive atmosphere for donors and patients.

Key words: Allogeneic Hematopoietic Stem Cell Transplantation, Related Donor, Qualitative Study, Nursing Care

摘要：

目的 了解异基因造血干细胞亲缘供者捐献过程中真实心理感受,为临床护理工作提供参考。 方法 采用目的抽样法,选取2019年3月—4月在北京市某三级甲等医院骨髓移植中心捐献异基因造血干细胞亲缘供者作为研究对象,由2名接受过访谈培训的护士对其进行半结构访谈。访谈内容由录音记录,信息饱和时终止访谈,本研究共纳入18名亲缘供者,通过Colaizzi 7步资料分析法分析资料。结果 访谈内容归纳为5个主题：决定捐献的动因、捐献给亲缘供者身体与心理带来不适、面临工作及家庭等各方面的压力、存在不被重视感、捐献产生积极影响。结论 在捐献过程中,亲缘供者常承受生理、心理、生活等多方面的压力,存在不被重视感,医护人员须加强与捐献者沟通,并给予更全面的专业指导,为亲缘供者捐献造血干细胞营造积极的氛围。

关键词: 异基因造血干细胞移植, 亲缘供者, 质性研究, 护理