Abstract:

Objective Meta-analysis was used to evaluate the effect of the solution-focused brief therapy on improving the anxiety and depression status of patients with HIV/AIDS. Methods Computer search of PubMed，Embase，Web of Science，Cochrane Library，CINAHL，PsycINFO，Chinese Biomedical Literature Database，China National Knowledge Infrastructure，Wanfang Database，CQVIP were conducted，and the search time frame was from the establishment of databases until April 9，2023. There were 2 investigators who independently screened the literature according to inclusion and exclusion criteria，extracted data and performed quality evaluation，and performed Meta-analysis using RevMan 5.4 software. Results A total of 11 publications were included，including 9 randomized controlled trials and 2 quasi-experimental studies，with a total of 1 219 patients with HIV/AIDS. Meta-analysis results showed that solution-focused brief therapy reduced anxiety scores（SMD=-1.89；95%CI：-2.79~-0.99，P<0.001），depression scores（SMD=-2.45；95%CI：-3.51~-1.39，P<0.001）. Subgroup analysis showed that improved anxiety（SMD=-4.16；95%CI：-7.97~-0.35，P<0.001），depression（SMD=-5.69；95%CI：-11.20~-0.19，P<0.001）in pregnant HIV/AIDS patients was significantly better than that in ordinary patients. Conclusion Solution-focused brief therapy is effective in improving anxiety and depression levels in patients with HIV/AIDS，and the application of this model in pregnant patients with HIV/AIDS has a more significant improvement effect，but high-quality，multicenter，large-sample clinical trial studies are needed to further confirm this conclusion in the future.

Key words: Solution-Focused Brief Therapy, Brief Psychotherapies, Acquired Immunodeficiency Syndrome, Anxiety, Depression, Meta-Analysis, Psychological Nursing

摘要：

目的 采用Meta分析评价聚焦解决模式改善HIV感染者/AIDS患者焦虑、抑郁状态的效果。 方法 计算机检索PubMed、Embase、Web of Science、Cochrane Library、CINAHL、PsycINFO、中国生物医学文献数据库、中国知网、万方数据库及维普数据库，检索时限为建库至2023年4月9日。由2名研究者独立按照纳入与排除标准筛选文献，提取资料并进行质量评价，采用RevMan 5.4软件进行Meta分析。 结果 共纳入11篇文献，9篇随机对照试验、2篇类实验研究，共1 219例HIV感染者/AIDS患者。Meta分析结果显示，聚焦解决模式能降低HIV感染者/AIDS患者的焦虑得分（SMD=-1.89；95%CI为-2.79~-0.99，P<0.001）、抑郁得分（SMD=-2.45；95%CI为-3.51~-1.39，P<0.001）。亚组分析结果显示，与普通患者相比，合并妊娠的HIV感染者/AIDS患者的焦虑（SMD=-4.16；95%CI为-7.97~-0.35，P<0.001）、抑郁（SMD=-5.69；95%CI为-11.20~-0.19，P<0.001）改善效果更加明显。 结论 聚焦解决模式可以有效改善HIV感染者/AIDS患者焦虑、抑郁水平，在妊娠合并HIV感染者/AIDS患者中应用该模式改善效果更加显著，但未来仍需高质量、多中心、大样本的临床试验研究进一步证实。

关键词: 聚焦解决模式, 短期心理疗法, 艾滋病, 焦虑, 抑郁, Meta分析, 心理护理学