1例原发性Ⅰ型高草酸尿症患儿行肝移植术后的护理

doi:10.3761/j.issn.0254-1769.2026.20.012

中华护理杂志 ›› 2026, Vol. 61 ›› Issue (20): 2824-2828.DOI: 10.3761/j.issn.0254-1769.2026.20.012

1例原发性Ⅰ型高草酸尿症患儿行肝移植术后的护理

吴君(), 卢芳燕^*()

浙江大学医学院附属第一医院肝移植中心杭州市 310009

收稿日期:2025-12-12 出版日期:2026-10-20 发布日期:2026-10-12
*通讯作者: 卢芳燕，E-mail：2196032@zju.edu.cn
作者简介:吴君：女，本科，主管护师，E-mail：392040973@qq.com
第一联系人：作者贡献声明
吴君：选题设计、资料收集、文献检索、论文撰写；卢芳燕：论文审阅和修改
基金资助:
2025年度浙江大学医学院附属第一医院护理学科建设科研项目(ZD-ZYHL-2504)

Nursing care of a pediatric patient with primary type 1 hyperoxaluria after liver transplantation

WU Jun(), LU Fangyan^*()

Liver Transplantation Center， the First Affiliated Hospital，Zhejiang University School of Medicine， Hangzhou 310009， China

Received:2025-12-12 Online:2026-10-20 Published:2026-10-12
* Corresponding author: LU Fangyan，E-mail：2196032@zju.edu.cn
Funding program:
2025 Nursing Discipline Construction Research Project of the First Affiliated Hospital of Zhejiang University School of Medicine(ZD-ZYHL-2504)

摘要/Abstract

摘要：

总结1例原发性Ⅰ型高草酸尿症患儿行肝移植的术后护理经验。护理要点：精准抗凝联合多维出血评估，预警隐匿性出血的发生；制订精细化容量管理方案，维持血流动力学稳定，保证移植肝有效灌注；降阶梯肾脏替代治疗，预防草酸中毒及透析并发症；实施分阶段营养支持，缓解高草酸血症，治疗乳糜漏；开展个体化随访管理，优化器官功能，为序贯肾移植创造条件。经过精心护理，53 d后患儿顺利出院，随访90 d，移植肝功能稳定，经规律血液透析，尿草酸含量稳步下降，进入儿童肾移植等待排序。

关键词: 高草酸尿症, 肾功能衰竭, 肝移植, 儿科护理学

Abstract:

This paper summarizes the postoperative nursing experience of a child with primary hyperoxaluria type Ⅰ who underwent liver transplantation. The key nursing measures were as follows：precise a anticoagulation combined with multi-dimensional bleeding assessment to early warn the occurrence of occult bleeding；a refined volume management strategy was formulated to maintain circulatory stability and ensure adequate perfusion of the transplanted liver；implementing de-escalation renal replacement therapy to prevent oxalate intoxication and dialysis-related complications；adopting phased nutritional support to alleviate hyperoxalemia and treat chylous leakage；and conducting individualized follow-up management to optimize organ function and create favorable conditions for sequential kidney transplantation. With meticulous nursing interventions，the child recovered and was discharged from hospital. During a 90-day follow-up，the function of the transplanted liver remained stable；the child received regular hemodialysis；the urinary oxalate level decreased steadily；the child was enrolled in the waiting list for pediatric kidney transplantation.

Key words: Hyperoxaluria, Renal Failure, Liver Transplantation, Pediatric Nursing

吴君, 卢芳燕. 1例原发性Ⅰ型高草酸尿症患儿行肝移植术后的护理[J]. 中华护理杂志, 2026, 61(20): 2824-2828.

WU Jun, LU Fangyan. Nursing care of a pediatric patient with primary type 1 hyperoxaluria after liver transplantation[J]. Chinese Journal of Nursing, 2026, 61(20): 2824-2828.

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1例原发性Ⅰ型高草酸尿症患儿行肝移植术后的护理

Nursing care of a pediatric patient with primary type 1 hyperoxaluria after liver transplantation

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