淋巴瘤患者化疗随访方案的构建及应用研究

doi:10.3761/j.issn.0254-1769.2026.06.001

摘要/Abstract

摘要：

目的构建淋巴瘤患者化疗随访方案并探讨其应用效果，旨在为规范其随访提供参考。方法以互动式患者参与患者安全理论框架为基础，通过文献检索、半结构式访谈、专家函询及预试验，构建淋巴瘤患者化疗随访方案。采用连续抽样法，选取2023年7—11月福建省某三级甲等综合医院收治的65例淋巴瘤患者作为研究对象，将2023年9—11月收治的患者作为试验组，采用淋巴瘤患者化疗随访方案进行随访，将2023年7—8月收治的患者作为对照组，进行常规随访，共随访3个化疗周期，比较两组自我护理能力、治疗依从性、焦虑抑郁评分、随访满意度等指标的差异。结果研究过程中共脱落4例患者，最终试验组纳入32例、对照组纳入29例。随访结束后，试验组的自我护理能力、治疗依从性、随访满意度均高于对照组，焦虑抑郁评分低于对照组，差异具有统计学意义（均P<0.05）。结论淋巴瘤患者化疗随访方案具有较好的科学性和可行性，实施该方案可提高患者的自我护理能力，提升患者的治疗依从性和随访满意度，并改善其焦虑抑郁情况。

关键词: 淋巴瘤, 化疗, 患者参与, 随访, 肿瘤护理

Abstract:

Objective To develop a follow-up protocol for lymphoma patients undergoing chemotherapy and to evaluate its application effects，aiming to provide a reference for standardizing lymphoma follow-up practice. Methods Guided by the theoretical framework of “interactive patient participation in patient safety”，a follow-up protocol was developed through literature review，semi-structured interviews，expert consultation，and a pilot test. Using consecutive sampling，65 lymphoma patients hospitalized in a tertiary grade A general hospital in Fujian Province from July to November 2023 were recruited. Patients admitted from September to November 2023 were assigned to an experimental group and received the developed follow-up protocol，while those admitted from July to August 2023 were assigned to a control group and received routine follow-up care. The follow-up lasted for 3 chemotherapy cycles. Differences in self-care ability，treatment compliance，anxiety and depression scores，and follow-up satisfaction were compared between the 2 groups. Results 4 patients dropped out during the study. Finally，32 patients in the experimental group and 29 in the control group completed the study. After the follow-up，the experimental group showed significantly higher scores in self-care ability，treatment compliance，and follow-up satisfaction，and significantly lower anxiety and depression scores compared to the control group（all P<0.05）. Conclusion The follow-up protocol for lymphoma patients undergoing chemotherapy demonstrates good scientific rigor and feasibility. The implementation of this protocol can improve patients’ self-care ability，enhance their treatment compliance and follow-up satisfaction，and alleviate their anxiety and depression.

Key words: Lymphoma, Chemotherapy, Patient Participation, Follow Up, Oncology Nursing

陈淑萍, 谢宝缘, 陈绵绵, 李美玲, 林翠芬. 淋巴瘤患者化疗随访方案的构建及应用研究[J]. 中华护理杂志, 2026, 61(6): 725-732.

CHEN Shuping, XIE Baoyuan, CHEN Mianmian, LI Meiling, LIN Cuifen. Development and application of a follow-up protocol for lymphoma patients undergoing chemotherapy[J]. Chinese Journal of Nursing, 2026, 61(6): 725-732.

图/表 3

表1 淋巴瘤患者化疗随访方案

Table 1 Follow-up implementation plan for lymphoma patients undergoing chemotherapy

表2 两组一般资料比较

Table 2 Comparison of general data between the 2 groups

表3 两组自我护理能力、焦虑抑郁评分比较（分）

Table 3 Comparison of the scores of self-care ability and anxiety and depression scores between the 2 groups（scores）

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