Objective To systematically review the effect of telemedicine on the prevention of pressure injury among community-dwelling patients with spinal cord injury,and to provide evidence-based bases for future research. Methods Both Chinese and English databases(CBM,CNKI,WanFang,VIP,Cochrane Library,PubMed,Embase,Web of Science,Scopus,ProQuest and BMJ Best Practice) were searched from their inception to August 2021. 2 researchers evaluated the quality of the included articles,and the meta-analysis was performed by RevMan 5.3 software. Results A total of 14 articles were included (9 randomized controlled trials and 5 quasi-experimental studies),with totally 1 582 community-dwelling patients with spinal cord injury. The results of meta-analysis showed that telemedicine can decrease the incidence of pressure injury in community-dwelling patients with spinal cord injury [RR=0.29,95%CI(0.20,0.43),P<0.001],improve the quality of life[SMD=0.94,95%CI(0.19,1.68),P=0.010] and satisfaction[SMD=0.86,95%CI(0.58,1.13),P<0.001],and the incidence of adverse events caused by pressure injury did not increase significantly[RR=0.50,95%CI(0.20,1.27),P=0.140]. Conclusion The current evidence shows that telemedicine could decrease the incidence of pressure injury,improve quality of life and satisfaction in community-dwelling patients with spinal cord injury,proving that telemedicine is safe and feasible. Due to the limited quality and quantity of included articles,the above conclusion needs to be verified by more high-quality studies.