Objective To compare the effects of three nursing methods in preventing neck skin injury of tracheotomy patients.Methods A total of 168 cases of tracheotomy patients were randomly divided into 3 groups with 56 cases in each group:the liner gauze(Group I),the hydrocolloid dressing(Group Ⅱ),and the liner foam dressing(Group Ⅲ). The incidence of neck skin injury,the service length of liner dressing,the time of dressing replacement,the difficulty of dressing replacement,and average cost were compared in three groups,and the effects of three nursing methods in preventing neck skin injury in tracheotomy patients were evaluated.Results There were 13 cases,5 cases,and 1 case of skin injury in group Ⅰ~Ⅲ,respectively. There was significant difference in the incidence and severity of skin injury among three groups (P<0.05). The service length of liner dressing from low to high was Group Ⅰ,Group Ⅱ and Group Ⅲ,respectively. The time spent in replacing dressing from low to high was Group Ⅲ,Group Ⅰ and Group Ⅱ,respectively. The difficulty of replacing dressing from low to high was Group Ⅲ,Group Ⅰ and Group Ⅱ,respectively. The average cost from low to high was Group I,Group II and Group III,respectively.Conclusion Foam dressing can effectively prevent neck skin injury in patients underwent tracheotomy,and it has long length of service,short replacement time,is easier to operate,and more suitable for patients with tracheotomy,but economic cost is slightly higher.