Objective To develop dietary nursing scheme for patients with dysphagia after first stroke,and to explore the effects of application.Methods From July 2017 to June 2018,60 patients with grade 3 or 4 dysphagia after the first stroke were conveniently selected from neurology department of a tertiary hospital. Thirty patients in Ward One were included in the experimental group,and 30 patients in Ward Two were included in the control group. The experimental group was given a home-based dietary nursing scheme,and the control group was given routine dietary guidance. Three months after discharge,incidence of inhaled pneumonia,swallowing function and quality of life in two groups were compared.Results Three months after discharge,there was a significant difference in the incidence of pneumonia between two groups(P<0.05). The score of swallowing function was significantly higher in the experimental group than that in the control group at 1 month and 3 months after discharge(P<0.05). One month after discharge,quality of life in terms of eating time,symptom rate,food selection,fear,mental health,fatigue degree,psychological burden,eating desire and social interaction in the experimental group were better than those in the control group,and the differences were statistically significant(P<0.05),but there were no significant differences in language communication and sleep between two groups(P>0.05). At 3 months after discharge,the experimental group was superior to the control group in eating time,symptom rate,food selection,fear,mental health,fatigue degree,psychological burden,eating desire,social interaction and sleep,and the differences were statistically significant(P<0.05). There was no significant difference in language communication between two groups(P>0.05).Conclusion The home-based dietary nursing scheme for patients with dysphagia after first stroke can effectively prevent the occurrence of inhaled pneumonia and improve swallowing function and quality of life.