Abstract:

Objective To develop an assessment scale of oropharyngeal candidiasis risks in HIV-infected patients，and to test its reliability and validity. Methods The draft of the assessment scale was constructed by the literature analysis method，Delphi consultations and analytic hierarchy process. Totally 231 HIV-infected patients in a tertiary A hospital of Hangzhou were recruited for questionnaire survey in October 2023 to January 2024. Results The scale includes 3 dimensions，including general factors，HIV related factors and oral related factors，12 first-level items and 21 second-level items. The Cronbach’s α coefficient of the scale was 0.813；the content validity index was 0.98；the correlation of each dimension was 0.574~0.733（P<0.05）. Confirmatory factor analysis showed that the 3 factor models fitted the data well. The critical value（30.5 points） of the scale was determined by ROC curve；the area under the curve was 0.909；the sensitivity of index system was 0.962，and specificity was 0.697. Conclusion The assessment scale of oropharyngeal candidiasis risks in HIV-infected patients has good reliability and validity，and it can be used as an auxiliary tool for effective identification and prediction of oropharyngeal candidiasis risk.

Key words: Human Immunodeficiency Virus, Candidiasis, Risk Assessment, Scale, Reliability, Validity, Nursing Care

摘要：

目的 编制HIV感染者继发口咽念珠菌病风险评估量表并验证其信效度。方法 通过文献分析法、德尔菲专家函询法和层次分析法形成量表初稿，采用便利抽样法，选取2023年10月—2024年1月杭州市某三级甲等综合医院收治的231例HIV感染者进行问卷调查，检测量表的信效度。结果 该量表包含一般因素、HIV相关因素和口腔相关因素3个维度，12个一级条目和21个二级条目。量表总的Cronbach’s α系数为0.813，内容效度指数为0.98，各维度的相关性为0.574~0.733（P<0.05）。验证性因子分析显示，量表模型适配度各检验量均在可接受范围，模型拟合良好。利用受试者操作特征曲线确定量表的临界值为30.5分，该曲线下面积为0.909，灵敏度和特异度分别为0.962和0.697。结论 HIV感染者继发口咽念珠菌病风险评估量表具有良好的信效度，可作为口咽念珠菌病风险有效识别和预测的辅助工具。

关键词: 人类免疫缺陷病毒, 念珠菌病, 风险评估, 量表, 信度, 效度, 护理