Abstract:

Objective To systematically evaluate the medication experience of patients with chronic multimorbidities and to provide a reference for developing precise intervention programs to improve the medication experience of patients with chronic multimorbidities. Methods PubMed，Cochrane Library，Web of Science，Embase，CINAHL，PsycINFO，CNKI，Wanfang database，VIP database，and Chinese biomedical literature database were searched from the year of database establishment to October 2022，and qualitative studies on medication experiences of patients with chronic multimorbidities were retrieved. The Joanna Briggs Institute Critical Appraisal Tool for qualitative research（2016） in Australia was used to evaluate quality of the studies. A meta-synthesis method was used to integrate the results. Results A total of 11 articles were included，and 56 research results were extracted and integrated into 12 new categories，which were summarized into 4 integrated results：poor sensory experience of drugs，negative emotional and related experiences，reflective and behavioral experiences，and multi-dimensional debugging to improve medication experience. Conclusion The medication experience of patients with chronic multimorbidities should receive extensive attention from society and medical workers，and future research should be conducted to improve the level of patients’ medication experience in 5 dimensions，including sensory experience，emotional experience，reflective experience，behavioral experience and associative experience，so as to provide a basis for further improving the medication experience of patients with chronic multimorbidities in China.

Key words: Chronic Multimorbidities, Medication Experience, Feelings, Medication Care, Qualitative Research, Meta-Synthesis

摘要：

目的 系统评价慢性病共病患者的用药体验，为解决慢性病共病患者用药问题、提升其用药体验提供参考。 方法 检索Web of Science、PubMed、Cochrane Library、Embase、CINAHL、PsycINFO、中国知网、万方数据库、维普数据库、中国生物医学文献数据库，检索年限为建库至2022年10月，检索慢性病共病患者用药体验的质性研究，依据2016版澳大利亚乔安娜布里格斯研究所循证卫生保健中心质性研究质量评价标准评价文献质量，采用Meta整合方法分析结果。 结果 共纳入11篇文献，提炼出56个研究结果，整合成12个新的类别，综合为4个整合结果：药物感官体验较差、消极的情感体验和关联体验、思考体验和行为体验、多维度调试提升用药体验。 结论 慢性病共病患者用药体验应得到社会及医护人员的广泛关注，未来可从感官体验、情感体验、思考体验、行为体验和关联体验5个维度，提升患者的用药体验水平，并注重患者的自身心理和行为调试，进一步完善国内慢性病共病患者的用药体验。

关键词: 慢性病共病, 用药体验, 感受, 用药护理, 质性研究, Meta整合