Effectiveness of management of medication compliance to antiretroviral therapy in HIV/AIDS patients：an overview of reviews

doi:10.3761/j.issn.0254-1769.2021.04.022

Abstract

Abstract:

Objective To overview the systematic reviews of effectiveness of management of medication compliance to antiretroviral therapy（ART） in HIV/AIDS patients. Methods CNKI,CBM,JBI,The Cochrane Library,databases were searched to identify the relevant systematic reviews. 2 researchers screened systematic reviews and extracted the data independently. AMSTAR 2 scale and GRADE system were used to assess the quality of included systematic reviews. Results A total of 16 systematic reviews were included in this study. Results showed that the quality of 12 systematic reviews were rated as very low,and the quality of 4 systematic reviews were rated as low. The application of mobile technology can improve medication adherence of HIV/AIDS patients, and the evaluation methods of medication adherence are diverse. Conclusion The application of mobile technology can improve medication adherence of HIV/AIDS patients. However,existing studies are insufficient. The overall effectiveness of management of medication compliance to ART in HIV/AIDS patients needs to be further explored and validated by subsequent high-quality and large-sample studies.

Key words: Acquired Immunodeficiency Syndrome, Antiretroviral Therapy, Medication Adherence, Systematic Reviews, Meta-Analysis, Nursing Care

摘要：

目的对接受抗病毒治疗（antiretroviral therapy,ART）的HIV感染者/AIDS患者服药依从性管理的系统评价进行再评价。方法 2020年8月,计算机检索中国知网、中国生物医学文献数据库以及乔安娜布里格斯研究所、The Cochrane Library等数据库,检索HIV感染者/AIDS患者ART服药依从性管理的系统评价,由2名研究成员独立进行文献筛选、资料提取,分别对纳入的系统评价和结局指标进行质量评价。结果共纳入16篇系统评价,评价结果显示,12篇质量等级为极低,4篇质量等级为低。结果显示,移动技术干预方法能提高HIV感染者/AIDS患者的服药依从性,服药依从性的评价方法多元。结论移动技术可提高HIV感染者/AIDS患者的服药依从性,但现存的证据不足,HIV感染者/AIDS患者ART服药依从性管理的总体效果需进一步探讨,后续仍需要高质量、大样本的研究来进一步验证。

关键词: 获得性免疫缺陷综合征, 抗逆转录病毒疗法, 服药依从性, 系统评价, Meta分析, 护理

GAO Yan, ZHANG Qing, SUN Meiyan, ZHANG Lin, LU Hongzhou. Effectiveness of management of medication compliance to antiretroviral therapy in HIV/AIDS patients：an overview of reviews[J]. Chinese Journal of Nursing, 2021, 56(4): 604-610.

高岩, 章清, 孙美艳, 张林, 卢洪洲. HIV感染者/AIDS患者服药依从性管理的系统评价再评价[J]. 中华护理杂志, 2021, 56(4): 604-610.

Figures/Tables 3

References 32

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