Abstract:

Objective To analyze effects of system management in patients with Crohn’s disease.Methods A self-comparison method was adopted in this study. A total of 45 patients with Crohn’s disease were recruited from Department of Gastroenterology,Peking Union Medical College Hospital. Nutritional management was applied during enteral nutrition therapy. Nutrition status and adverse effects were recorded on the day of enrollment,1 month,3 months and 6 months after receiving enteral nutrition,respectively. Repeated measures ANOVA was used to analyze the differences of evaluation indicators at different time points.Results After 6 months of interventions,nutritional indicators（weight,NRS2002,TP,Alb,HGB） were significantly increased,while inflammatory indicators（ESR,hsCRP） were significantly decreased（P<0.05）. The incidences of intestinal symptoms and adverse reactions decreased gradually.Conclusion Nutritional management based on the system management theory can effectively improve the nutrition status of patients and the quality of care.

Key words: Enteral Nutrition, Crohn’s Disease;, Nutritional Status, Nursing Care

摘要：

目的 探讨系统管理在克罗恩病患者肠内营养护理中的应用效果。方法 采用自身前后对照设计。便利抽取北京市某三级甲等医院消化内科45例住院克罗恩病患者,实施肠内营养系统管理,评估患者接受肠内营养治疗基线、干预后1个月、3个月、6个月营养状况及不良反应等。采用重复测量资料分析方法分析不同时间点评估指标差异。结果 经过6个月干预,营养状况相关指标（体重、营养风险筛查评分、总蛋白、白蛋白、血红蛋白）均有明显升高,炎性指标（血沉、C反应蛋白）均有明显降低（P<0.05）,肠道症状及不良反应发生率逐渐降低。结论 克罗恩病患者肠内营养系统管理能够有效改善患者的营养状况,提高患者依从性,改善营养护理工作质量。

关键词: 肠内营养, 克罗恩病, 营养状况, 护理