专科护士主导的营养管理方案在诱导缓解化疗期白血病患儿中的应用研究

doi:10.3761/j.issn.0254-1769.2024.23.013

摘要/Abstract

摘要：

目的探讨专科护士主导的营养管理方案对诱导缓解化疗期白血病患儿营养状况的影响。方法采用便利抽样法，选取2023年12月—2024年5月在四川省某三级甲等医院接受诱导缓解化疗的45例白血病患儿作为试验组，实施专科护士主导的营养管理方案；选取2023年8月—11月在该院接受诱导缓解化疗的45例白血病患儿作为对照组，实施常规护理，干预时长为45 d。比较两组的中上臂围、体重指数、白蛋白浓度、前白蛋白浓度以及患儿家长的满意度。结果研究过程中失访2例，最终试验组、对照组均纳入44例。干预后，试验组的中上臂围、体重指数、白蛋白浓度均高于对照组，差异具有统计学意义（P<0.05）；两组前白蛋白浓度比较，差异无统计学意义（P=0.199）；试验组患儿家长的满意度高于对照组，差异具有统计学意义（P<0.001）。结论实施专科护士主导的营养管理方案有助于改善诱导缓解化疗期白血病患儿的中上臂围及体重指数，提升白蛋白浓度、患儿家长的满意度。

关键词: 白血病, 诱导缓解, 化疗, 营养管理, 儿科护理学

Abstract:

Objective To explore the effects of a specialist nurse-led nutrition management program on the nutritional status of children with leukemia during induction remission chemotherapy. Methods Using the convenience sampling method，45 children with leukemia who received induction remission chemotherapy in a tertiary hospital in Sichuan Province from December 2023 to May 2024 were selected as an experimental group，and the specialist nurse-led nutrition management program was implemented. A total of 45 children with leukemia who admitted to the same hospital to receive induction remission chemotherapy from August to November 2023 were selected as a control group，and routine nursing care was provided. The duration of the intervention was 45 days，and the children’s mid-upper arm circumference，BMI，serum albumin and pre-protein concentration were compared between the 2 groups before and after the intervention，and post-intervention satisfaction of their parents was also compared. Results 2 cases were lost to follow-up during the study，and finally 44 cases were included in both the experimental group and the control group. After the intervention，mid-upper arm circumference，BMI，and serum albumin concentration in the experimental group were higher than those in the control group，with statistically significant differences（P<0.05）；there was no significant difference in pre-protein concentration between the 2 groups（P=0.199）；the satisfaction of parents in the experimental group was higher than that in the control group，and the difference was statistically significant（P<0.001）. Conclusion Implementation of a specialist nurse-led nutrition management program is helpful in improving mid-upper arm circumference and BMI in children with leukemia during induction and remission chemotherapy，as well as their serum albumin concentration and parental satisfaction.

Key words: Leukemia, Induction Remission, Chemotherapy, Nutrition Management, Pediatric Nursing

毛琴, 毛孝容, 李鑫, 唐莉, 陈秋蓉, 谢帅, 李玥, 张娴. 专科护士主导的营养管理方案在诱导缓解化疗期白血病患儿中的应用研究[J]. 中华护理杂志, 2024, 59(23): 2900-2907.

MAO Qin, MAO Xiaorong, LI Xin, TANG Li, CHEN Qiurong, XIE Shuai, LI Yue, ZHANG Xian. Application of a specialist nurse-led nutrition management program in children with leukemia during induction remission chemotherapy[J]. Chinese Journal of Nursing, 2024, 59(23): 2900-2907.

图/表 3

表1 专科护士主导的营养管理方案

Table 1 Specialized nurse-led nutrition management program

表2 两组一般资料比较

Table 2 Comparison of general information between the 2 groups

表3 两组营养指标比较

Table 3 Comparison of nutritional indicators between the 2 groups

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