虚拟认知康复训练在乳腺癌化疗相关认知障碍患者中的应用

doi:10.3761/j.issn.0254-1769.2019.05.005

摘要/Abstract

摘要：

【目的】探索虚拟认知康复训练对改善乳腺癌化疗相关认知障碍患者认知功能和日常生活能力的效果。【方法】通过虚拟认知康复训练系统,对80例乳腺癌化疗相关认知障碍患者进行认知干预训练,在干预训练前后运用蒙特利尔认知评估量表、日常生活能力量表和半结构式访谈来评价虚拟认知康复训练的临床疗效。【结果】与干预前比较,干预8周后,患者蒙特利尔认知评估量表得分明显提高,差异具有统计学意义（P<0.05）;日常生活能力量表得分低于干预前,差异具有统计学意义（P<0.05）。患者均对虚拟认知康复训练能提高认知功能给予肯定,并表示愿意继续进行虚拟认知康复训练。【结论】虚拟认知康复训练可以改善乳腺癌化疗相关认知障碍患者的认知功能,提高其日常生活能力。

关键词: 乳腺肿瘤, 化学疗法, 肿瘤, 局部灌注, 认知障碍, 虚拟认知康复训练

Abstract:

Objective To explore the effect of virtual cognitive rehabilitation training on cognitive function and activities of daily living among breast cancer patients with cognitive impairment.Methods Eighty breast cancer patients with cognitive impairment after chemotherapy received cognitive intervention training. Before and after intervention,clinical effects of virtual cognitive rehabilitation training were evaluated by Montreal Cognitive Assessment scale,Activity of Daily Living Scale,Mini-Mental State scale,and semi-structured interviews.Results After 8-week-intervention,the scores of the Montreal Cognitive Assessment Scale increased significantly,and the difference was statistically significant （P<0.05）. After intervention,the scores of ADL were lower than those before intervention,and the difference was statistically significant （P<0.05）. All patients gave recognition of effects of virtual cognitive rehabilitation training on improving cognitive function,while they were willing to continue this training.Conclusion Virtual cognitive rehabilitation training can improve cognitive function and daily life ability of breast cancer patients with cognitive impairment after chemotherapy.

Key words: Breast Neoplasms, Chemotherapy, Cancer, Regional Perfusion, Cognition Disorders, Virtual Cognitive Rehabilitation Training

陈肖敏,金艾香,朱慧,张丹妮. 虚拟认知康复训练在乳腺癌化疗相关认知障碍患者中的应用[J]. 中华护理杂志, 2019, 54(5): 664-667.

CHEN Xiaomin,JIN Aixiang,ZHU Hui,ZHANG Danni. Application and effect of virtual cognitive rehabilitation training in breast cancer patients with cognitive impairment after chemotherapy[J]. Chinese Journal of Nursing, 2019, 54(5): 664-667.

图/表 2

参考文献 18

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项目	例数	视空间/执行能力	命名	注意	语言	抽象思维	延迟回忆	定向力	总分
干预前	80	2.53±0.92	1.87±0.93	4.38±1.25	1.69±0.71	0.91±0.69	1.69±1.11	4.33±1.12	17.41±2.15
干预后	78	4.63±0.54	2.69±0.54	5.59±0.50	2.62±0.56	1.62±0.49	4.00±0.79	5.08±0.73	26.22±1.42
t值		-18.548	-7.740	-9.215	-10.842	-8.218	-13.855	-7.511	-28.739
P值		<0.001	<0.001	<0.001	<0.001	<0.001	<0.001	<0.001	<0.001

项目	例数	视空间/执行能力	命名	注意	语言	抽象思维	延迟回忆	定向力	总分
干预前	80	2.53±0.92	1.87±0.93	4.38±1.25	1.69±0.71	0.91±0.69	1.69±1.11	4.33±1.12	17.41±2.15
干预后	78	4.63±0.54	2.69±0.54	5.59±0.50	2.62±0.56	1.62±0.49	4.00±0.79	5.08±0.73	26.22±1.42
t值		-18.548	-7.740	-9.215	-10.842	-8.218	-13.855	-7.511	-28.739
P值		<0.001	<0.001	<0.001	<0.001	<0.001	<0.001	<0.001	<0.001

项目	例数	基本性日常生活能力	工具性日常生活能力	总分
干预前	80	6.86±1.38	13.94±1.42	20.79±1.88
干预后	78	4.72±1.69	11.33±1.43	16.05±2.26
t值		9.653	12.894	16.361
P		<0.001	<0.001	<0.001

项目	例数	基本性日常生活能力	工具性日常生活能力	总分
干预前	80	6.86±1.38	13.94±1.42	20.79±1.88
干预后	78	4.72±1.69	11.33±1.43	16.05±2.26
t值		9.653	12.894	16.361
P		<0.001	<0.001	<0.001