Objective To construct an intelligent postoperative rehabilitation management platform and evaluate its effect in patients with head and neck cancer. Methods The postoperative intelligent rehabilitation management platform of head and neck cancer patients was divided into 5 layers from bottom to top,including the underlying environment, platform support, core database, analysis algorithm and application platform. Through the construction of head and neck tumor postoperative complications knowledge base and risk prediction model and wearable device auxiliary precision prediction risk,the head and neck cancer patients with postoperative intelligent rehabilitation management was realized. A historical controlled study was conducted and 90 participants with head and neck cancer were selected who underwent the surgical treatment in a hospital in Hangzhou,Zhejiang Province. The experimental group(45 participants admitted from February to July) received the intervention by the intelligent rehabilitation management platform,while the control group(45 patients from August to December) received the routine rehabilitation management. The outcome measures including NRS scores at 12 h,24 h,48 h and 72 h after surgery,incidence of postoperative complications,postoperative length of hospital stay,and patient satisfaction were compared between the 2 groups. Results The scores of incidences of complications,postoperative hospital stay,and NRS scores at 12 h,24 h,48 h and 72 h after surgery in the experimental group were lower than those in the control group(P<0.05),while the scores of patient satisfaction in the experimental group were higher than those of the control group(P<0.05). Conclusion The intelligent postoperative rehabilitation management platform can achieve accurate prediction of postoperative complications,reduce postoperative complications of head and neck tumors,timely intervene to relieve patients’ pain and discomfort,shorten hospital stays,improve nursing work efficiency and improve patient satisfaction.