Objective To evaluate the effect of threshold-pressure inspiratory muscle training on pulmonary rehabilitation and quality of life in asthma patients by meta-analysis. Methods We searched the Cochrane Library,PubMed,Embase,Web of Science,Wanfang,CNKI,VIP,and CBM databases for randomized controlled trial studies on the effects of inspiratory muscle training on pulmonary rehabilitation and quality of life in patients with asthma. The search time is from the establishment of databases to January 6,2021. After the quality evaluation,meta-analysis was performed using RevMan 5.3 software. Results A total of 10 publications including 456 patients were included,and the meta-analysis showed that threshold-pressure inspiratory muscle training improved patients’ forced vital capacity[SMD=0.90,95%CI（0.68,1.11）,P<0.001],forced expiratory volume in a second[SMD=0.62,95%CI（0.41,0.83）,P<0.001],peak expiratory flow [WMD=0.32,95%CI（0.01,0.62）,P=0.040],maximum voluntary ventilation[WMD=11.89,95%CI（6.42,17.37）,P<0.001],and maximum inspiratory pressure[SMD=29.76,95%CI（18.15,41.36）,P<0.001],reduced their dyspnea[SMD=-0.51,95%CI（-0.95,-0.06）,P<0.001],and increased their 6-min walk distance[WMD=77.13,95%CI（24.58,129.67）,P=0.004]. However,the difference in improving their quality of life was not statistically significant[SMD=1.21,95%CI（-2.11,4.52）,P=0.480]. Conclusion Threshold-pressure inspiratory muscle training can significantly improve patients’ lung function indicators,enhance respiratory muscle strength,reduce dyspnea,and increase 6-min walking distance in asthmatic patients,but the effect in improving quality of life is not significant,and more clinical high-quality studies need to further verify its effectiveness.
