Abstract:

Objective To explore the effect of five-element corresponding to five-color music therapy on post-stroke subthreshold depression patients and provide references for expanding their non pharmacological management in traditional Chinese medicine. Methods Convenience sampling was used to select 68 patients with post-stroke subthreshold depression admitted to the neurology department of a tertiary comprehensive hospital in Zhejiang Province from May to November 2024 as the research subjects. They were randomly divided into an experimental group and a control group using a random number table，with 34 patients in each group. The experimental group received five-element corresponding to five-color music therapy intervention，while the control group received five-element music therapy with an intervention period of 2 weeks. The Hamilton Depression Scale-17 Items（HAMD-17） and the Center for Epidemiological Studies Depression Scale（CES-D） were used to evaluate patients within 24 hours of enrollment，1 week after intervention，and 2 weeks after intervention，respectively. Results A total of 67 patients completed the study，with 34 in the experimental group and 33 in the control group. The repeated measures of variance results showed that there was an interaction between the HAMD-17 and CES-D scores of the 2 groups（P<0.001）. The HAMD-17 and CES-D scores of the experimental group after 1 and 2 weeks of intervention were lower than those of the control group，and the differences were statistically significant（P<0.05）. Conclusion The intervention of five-element corresponding to five-color music therapy on post-stroke subthreshold depression patients can effectively improve the depressive mood，and is worthy of clinical promotion.

Key words: Five-Element Corresponding to Five-Color, Music Therapy, Stroke, Subthreshold Depression, Traditional Chinese Medicine Nursing

摘要：

目的 探讨五音配五色音乐疗法在脑卒中后阈下抑郁患者中的应用效果，为拓展其中医非药物管理提供参考依据。 方法 采用便利抽样法，选取2024年5—11月浙江省某三级甲等综合医院神经内科住院的68例脑卒中后阈下抑郁患者作为研究对象，采用随机数字表法分为试验组和对照组，每组各34例。试验组采用五音配五色音乐疗法干预，对照组给予五音疗法，干预周期为2周。采用汉密尔顿抑郁量表-17（Hamilton Depression Scale-17 Items，HAMD-17）、流调中心抑郁量表（Center for Epidemiological Studies Depression Scale，CES-D）分别在患者入组24 h内以及干预1、2周后进行评估。 结果 共67例患者完成研究，试验组34例，对照组33例。重复测量方差分析结果显示，两组HAMD-17、CES-D得分存在交互作用（P<0.001），干预1、2周后，试验组的HAMD-17、CES-D得分低于对照组，差异具有统计学意义（均P<0.05）。 结论 五音配五色音乐疗法可有效改善脑卒中后阈下抑郁患者的抑郁情绪，值得临床推广。

关键词: 五音配五色, 音乐疗法, 脑卒中, 阈下抑郁, 中医护理学