Abstract:

Objective The researchers systematically retrieved，evaluated，and summarized the best evidence for the care of nebulized inhalation in adult patients on mechanical ventilation，to provide a basis for standardizing the care of nebulized inhalation in patients on mechanical ventilation. Methods We systematically searched the domestic and foreign databases to collect the evidence on the literature related to nebulization therapy for mechanical ventilation in adults. The time for the retrieval is from the inception of databases until February 2023. There were 3 researchers who evaluated the quality of the literature，and extracted and summarized the evidence based on this subject. Results A total of 19 articles were obtained in database. 42 pieces of evidence were summarized，covering pre-assessment of nebulized inhalation，preparation before nebulized inhalation，medication management，selection and standardized use of nebulization devices，respiratory machine mode and parameter settings，equipment management during nebulized inhalation，evaluation of effect，management of adverse reactions，disposal of materials and environment after nebulized inhalation and management of nebulized inhalation for respiratory infectious diseases. Conclusion This study summarized the best evidence for nebulized inhalation nursing in adult patients with mechanical ventilation，so as to provide a reference of standardized nebulized inhalation therapy for such patients，which is conducive to ensuring the safety of patients.

Key words: Adults, Mechanical Ventilation, Nebulized Inhalation, Summary of Evidence, Evidence-Based Nursing

摘要：

目的 系统检索、评价并汇总成人机械通气患者雾化吸入护理的最佳证据，为规范机械通气患者雾化吸入护理提供依据。 方法 计算机检索中英文数据库中与成人机械通气雾化吸入护理相关的文献，检索时限为建库至2023年2月，由3名研究人员对纳入文献进行质量评价、证据提取并进行证据汇总分级。 结果 共纳入19篇文献，汇总了42条证据，涉及雾化吸入前评估、雾化吸入前准备、用药管理、雾化装置的选择和规范使用、呼吸机模式及参数设置、雾化吸入过程中的设备管理、效果评价、不良反应的处理、雾化吸入后用物及环境处置、呼吸道传染性疾病雾化吸入的管理10个方面。 结论 该研究整理并汇总了成人机械通气患者雾化吸入护理的最佳证据，内容科学、全面，可为规范此类患者的雾化吸入提供参考，保障患者安全。

关键词: 成人, 机械通气, 雾化吸入, 证据总结, 循证护理学