Abstract:

Objective To search，evaluate and summarize the best evidence of assessment and nursing for hemorrhagic cystitis patients undergoing hematopoietic stem cell transplantation，so as to provide a reference for clinical practice. Methods Evidence-based method was used to search the relevant literature according to the "6S" evidence pyramid model. The time limit for the literature search is from the inception of databases until May 30，2022. Results A total of 14 pieces of literature were included，including 1 clinical decisional support，2 guidelines，1 best practice report，3 consensuses，7 systematic reviews. Totally 23 pieces of evidence were summarized with 6 topics，including assessment of risk factors，auxiliary examination assessment，symptom assessment，lifestyle guidance，medication-based prevention，and comprehensive intervention. Conclusion This study summarizes the best available evidence for the assessment and nursing for hemorrhagic cystitis patients undergoing hematopoietic stem cell transplantation. It is recommended that health care providers should fully consider the actual situation of patients，in order to correct assessment and effective intervention.

Key words: Hematopoietic Stem Cell Transplantation, Hemorrhagic Cystitis, Nursing Assessment, Evidence-Based Nursing

摘要：

目的 检索造血干细胞移植后并发出血性膀胱炎患者护理评估和干预的相关证据，并对最佳证据进行总结，为临床实践提供参考。 方法 应用循证方法，遵循“6S”证据金字塔模型检索相关文献，检索时限为建库至2022年5月30日。采用乔安娜布里格斯研究所循证卫生保健中心的文献质量评价标准和证据分级系统，对纳入文献进行质量评价及证据级别评定。 结果 共纳入14篇文献，其中临床决策1篇、指南2篇、最佳实践1篇、专家共识3篇、系统评价7篇。总结的最佳证据包括危险因素评估、辅助检查评估、症状体征评估、生活方式指导、药物干预、综合干预6个方面，共23条。 结论 该研究总结了造血干细胞移植后并发出血性膀胱炎患者护理评估和干预的最佳证据，建议护理人员在应用证据时，充分考虑患者的实际情况，进行正确评估和有效干预。

关键词: 造血干细胞移植, 出血性膀胱炎, 护理评估, 循证护理学