Abstract:

Objective To explore the current situation of medication safety behavior of elderly cancer patients and the path relationship of various influencing factors for improving medication safety behavior. Methods A total of 340 elderly cancer patients were investigated by a demographic questionnaire，the Medication Safety Behavior Scale，the Medication Literacy Scale，the Family Care Index Questionnaire，and the Chinese version of the Empowerment Scale for Cancer Patients from August to December 2024. The multiple linear regression analysis was applied to analyze influencing factors，and data were analyzed using SmartPLS 4.0 to construct a partial least squares structural equation model with path analysis. Results A total of 307 valid questionnaires were collected. The mean medication safety behavior score was 31.89 ± 5.38. Residential area，drug literacy，family care，and health empowerment are factors that affect medication safety in elderly cancer patients，accounting for 37.3% of the total variation. The path analysis results indicated that health empowerment（β=0.480），medication literacy（β=0.154），and family care（β=0.227） positively correlate with medication safety behavior. Health empowerment played a partial mediating role between family care and medication safety behavior，as well as between medication literacy and medication safety behavior. The mediating effects are 0.125 and 0.332（P<0.001），accounting for 35.51% and 68.31% of the total effect，respectively. Conclusion Medication safety behaviors among elderly cancer patients are at a median level and influenced by multiple factors. By improving their levels of health empowerment，healthcare professionals can motivate patients to take an active role in medication safety management. Further，promoting education on medication knowledge and teaching relevant medical skills，and together with guiding patients to perceive family care and support，can collectively improve their overall medication safety behaviors.

Key words: Cancer, Medication Safety Behaviors, Health Empowerment, Medication Literacy, Family Care, Pathway Analysis, Geriatric Care

摘要：

目的 探究老年肿瘤患者用药安全行为现状及影响因素的路径关系，为改善其用药安全行为提供参考。方法 采用便利抽样法，于2024年8—12月，应用一般资料调查表、老年慢性病患者安全用药行为问卷、老年慢性病患者药物素养量表、家庭关怀度指数问卷及中文版癌症患者赋权量表对江苏省某三级甲等医院的340例老年肿瘤患者进行调查，应用多元线性回归分析进行影响因素分析，通过SmartPLS 4.0软件构建偏最小二乘法结构方程模型并进行路径分析。结果 回收有效问卷307份。老年肿瘤患者用药安全行为得分为（31.89±5.38）分，居住地、药物素养、家庭关怀度、健康赋权是老年肿瘤患者用药安全行为的影响因素，共解释总变异的37.3%。路径分析结果显示，健康赋权（β=0.480）、药物素养（β=0.154）、家庭关怀度（β=0.227）正向影响老年肿瘤患者用药安全行为；健康赋权分别在家庭关怀度和用药安全行为、药物素养和用药安全行为间起部分中介作用，中介效应分别为0.125、0.332（P<0.001），占总效应的比例为35.51%、68.31%。结论 老年肿瘤患者用药安全行为处于中等水平，且受多种因素共同影响。医护人员可通过健康赋权激励老年肿瘤患者安全用药管理，加强药物知识与技能宣教，同时引导患者感知家庭关怀与支持，从而改善其用药安全行为。

关键词: 肿瘤, 用药安全行为, 健康赋权, 药物素养, 家庭关怀度, 路径分析, 老年护理