Abstract:

Objective To extract and summarize the best evidence related to constipation management in peritoneal dialysis patients，so as to provide bases for clinical medical staff to formulate peritoneal dialysis constipation assessment process and management plan. Methods We searched relevant guideline networks，UpToDate，BMJ，JBI，Cochrane Library，Web of Science，PubMed，Embase，CNKI，Wanfang databases to collect relevant guidelines，expert consensuses，best practices，recommended practices and systematic evaluations related to constipation management in peritoneal dialysis from the establishment of the database to March 18，2022. There were 2 researchers who independently evaluated the literature quality and extracted data. Results A total of 14 pieces of literature were included，including 4 guidelines，3 expert consensuses，2 best practices，2 systematic evaluations and 3 evidence summaries. Finally，22 pieces of best evidence including 4 dimensions were summarized，namely evaluation，health guidance，medication management and other treatments. Conclusion This study summarized the best evidence of constipation management in peritoneal dialysis patients，which can provide evidence-based bases for formulating constipation evaluation process，management plan and practice standard of peritoneal dialysis patients.

Key words: Peritoneal Dialysis, End-Stage Renal Disease, Constipation, Summary of Evidence, Evidence-Based Nursing

摘要：

目的 提炼并总结腹膜透析患者便秘管理的最佳证据，为临床医护人员制订腹膜透析患者便秘评估和管理方案提供依据。方法 系统检索国内外相关指南网站、UpToDate、BMJ Best Practice、乔安娜布里格斯研究所循证卫生保健中心数据库、Cochrane Library、Web of Science、PubMed、Embase、中国知网、万方数据库中与腹膜透析患者便秘管理相关的文献，包括最佳实践、推荐实践、指南、专家共识、证据总结、系统评价，检索时限为建库至2022年3月18日。由2名研究者独立对文献质量进行评价并提取资料。结果 共纳入14篇文献，包括指南4篇、专家共识3篇、最佳实践2篇、系统评价2篇、推荐实践3篇，总结的最佳证据包括评估、健康指导、用药管理、其他治疗4个方面，共22条。结论 该研究总结了腹膜透析患者便秘管理的最佳证据，可为制订腹膜透析患者便秘评估和管理方案、实践标准提供循证依据。

关键词: 腹膜透析, 终末期肾病, 便秘, 证据总结, 循证护理学