Abstract:

Objective To develop evidence-based clinical practice guideline（CPG） for multiple myeloma patients,and to provide references for improving clinical practice and promote the clinical outcome of patients. Methods Based on the theoretical framework of JBI evidence-based health care model,this guideline was formulated strictly in accordance with the methodology of developing evidence-based CPG. After a draft guideline was developed,it was appraised according to AGREE（Appraisal of Guidelines Research and Evaluation） Instrument. Then the CPG was finalized based on evaluation results and the advice of experts. Results The recommendations of the CPG involved the care for patients with anemia and bleeding,kidney injury,bone injury,infection prevention,chemotherapy toxicity,hematopoietic stem cell transplantation,amyloidosis,hyperviscosity and so on. Conclusion This nursing practice guideline for multiple myeloma was constructed on the basis of best evidence,Chinese clinical practice and professional judgments,which can provide valuable references for nursing decision-making on multiple myeloma patients care.

Key words: Multiple Myeloma, Nursing Care, Guideline

摘要：

目的 制定多发性骨髓瘤护理实践指南,为提高多发性骨髓瘤患者的护理质量、改善患者临床结局提供参考。 方法 以循证卫生保健模式为理论框架,严格按照循证护理实践指南制定的方法,构建《多发性骨髓瘤护理实践指南》草案,采用临床指南研究与评估系统Ⅱ对指南草案进行专家评审,根据专家评审结果和建议对指南进行修改,形成正式指南。结果 构建的指南推荐意见涵盖贫血与出血、肾功能损害、骨损伤、预防感染、化疗毒性反应观察与护理、造血干细胞移植护理、淀粉样变性、高粘滞血症、居家护理、心理护理10个方面的内容。结论 《多发性骨髓瘤护理实践指南》是根据最佳证据、我国临床实际情况以及专业人员判断而形成的循证指南,可为从事多发性骨髓瘤患者照护的护理人员进行科学决策提供实践依据。

关键词: 多发性骨髓瘤, 护理, 指南