关键词: 互联网, 肿瘤, 终末期, 社会心理干预, 主要照顾者, Meta分析, 循证护理学

Abstract:

Objective To evaluate the effect of Internet-based psychosocial intervention for primary caregivers of patients with terminal stage cancer. Methods The relevant randomized controlled trials of Internet-based psychosocial intervention for primary caregivers of patients with terminal stage cancer were systematically searched from 10 databases，such as Chinese Biomedical Literature Database，CNKI，PubMed，Embase and CINAHL and etc. The search period was from the establishment to December 18，2023，and 2 investigators screened the literature according to inclusion and exclusion criteria and extracted data. Cochrane Manual 5.1.0 was used to assess the quality of the literature. Meta-analysis was performed using Revman 5.4 software. Results A total of 9 pieces of the literature including 592 primary caregivers were included. Meta-analysis showed that Internet-based psychosocial intervention reduced the level of anxiety and depression for primary caregivers of patients with terminal stage cancer[MD=-1.64，95%CI（-2.68，-0.59），P=0.002] and the burden of care[SMD=-0.39，95%CI（-0.60，-0.18），P<0.001]，and improved quality of life[SMD=0.25，95%CI（0.01，0.48），P=0.040]；further research is needed to explore the effect of reducing the level of distress[MD=-0.88，95%CI（-1.91，0.16），P=0.100]. Conclusion The Internet-based psychosocial intervention is effective in improving the anxiety，depression and the burden of care of the primary caregivers of patients with terminal stage cancer，and it can improve the quality of life；further research is needed to explore the level of distress reduction.

Key words: Internet, Neoplasm, Terminal Stage, Psychosocial Interventions, Primary Caregiver, Meta-Analysis, Evidence-Based Nursing