1例弥漫性毒性甲状腺肿合并超敏反应综合征青少年患者的护理

doi:10.3761/j.issn.0254-1769.2026.09.014

中华护理杂志 ›› 2026, Vol. 61 ›› Issue (9): 1253-1256.DOI: 10.3761/j.issn.0254-1769.2026.09.014

1例弥漫性毒性甲状腺肿合并超敏反应综合征青少年患者的护理

夏云芳(), 王洪^*(), 崔岱, 付真真, 朱敏

南京医科大学第一附属医院内分泌科南京市 210029

收稿日期:2025-08-05 出版日期:2026-05-10 发布日期:2026-04-30
*通讯作者: 王洪，E-mail：wanghong1114@126.com
作者简介:夏云芳：女，本科，副主任护师，E-mail：2583647697@qq.com
第一联系人：作者贡献声明
夏云芳：参与临床实践、资料收集、论文撰写及修改；王洪：临床实践指导、论文修改；崔岱：论文审阅和修改；付真真：文献检索；朱敏：资料收集
基金资助:
湖南省三诺糖尿病公益基金会“甜蜜医生培育项目”(2023SD01)

Nursing care of an adolescent patient with Graves’ disease complicated by drug-induced hypersensitivity syndrome

XIA Yunfang(), WANG Hong^*(), CUI Dai, FU Zhenzhen, ZHU Min

Department of Endocrinology， the First Affiliated Hospital with Nanjing Medical University， Nanjing 210029， China

Received:2025-08-05 Online:2026-05-10 Published:2026-04-30
* Corresponding author: WANG Hong，E-mail：wanghong1114@126.com
Funding program:
Hunan Sinocare Diabetes Foundation “Sweet Doctor Training Project”(2023SD01)

摘要/Abstract

摘要：

总结1例弥漫性毒性甲状腺肿合并超敏反应综合征青少年患者的护理经验。护理要点：停止使用致敏药物，实施抗免疫药物精细管理；基于伯奇-沃托斯基点评分量表早期识别甲状腺危象，出现异常情况立即配合抢救；进行动态体温监测，采取多种策略联合降温；保护皮肤黏膜屏障功能，积极防控感染；实施以家庭为中心的健康教育，增强患者自我效能感与心理韧性。经过积极的治疗与精细化护理，患者于住院36 d后病情好转出院。出院后随访3个月，未发生药物超敏反应综合征相关免疫性后遗症。

关键词: 弥漫性毒性甲状腺肿, 药物超敏反应综合征, 青少年, 护理

Abstract:

This report summarizes the nursing experience of an adolescent patient with Graves’ disease complicated by drug hypersensitivity syndrome. Key nursing interventions included：prompt discontinuation of the causative drug and careful administration of immunosuppressive therapy；early identification of thyroid crisis using the Burch-Wartofsky scoring system，with immediate resuscitation initiated upon detection of abnormalities；conducting dynamic temperature monitoring and employing multiple combined cooling strategies；protecting skin and mucosal barrier function while actively preventing and controlling infections；implementing family-centered health education to enhance patients’ self-efficacy and psychological resilience. Following active treatment and meticulous care，the patient’s condition improved and they were discharged after 36 days of hospitalization. During the subsequent 3-month follow-up period，no immune-related sequelae associated with drug hypersensitivity syndrome occurred.

Key words: Graves’ Disease, Drug-Induced Hypersensitivity Syndrome, Adolescent, Nursing Care

夏云芳, 王洪, 崔岱, 付真真, 朱敏. 1例弥漫性毒性甲状腺肿合并超敏反应综合征青少年患者的护理[J]. 中华护理杂志, 2026, 61(9): 1253-1256.

XIA Yunfang, WANG Hong, CUI Dai, FU Zhenzhen, ZHU Min. Nursing care of an adolescent patient with Graves’ disease complicated by drug-induced hypersensitivity syndrome[J]. Chinese Journal of Nursing, 2026, 61(9): 1253-1256.

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1例弥漫性毒性甲状腺肿合并超敏反应综合征青少年患者的护理

Nursing care of an adolescent patient with Graves’ disease complicated by drug-induced hypersensitivity syndrome

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