中华护理杂志 ›› 2023, Vol. 58 ›› Issue (1): 98-104.DOI: 10.3761/j.issn.0254-1769.2023.01.014
杨俊琳(
), 杨健, 赵丽丽(
), 田玉梅, 宁艳花, 汤媛媛
收稿日期:2022-05-15
出版日期:2023-01-10
发布日期:2022-12-30
*通讯作者:
赵丽丽,E-mail:42566552@qq.com作者简介:杨俊琳:女,本科(硕士在读),护士,E-mail:y1359134648@163.com
基金资助:
YANG Junlin(
), YANG Jian, ZHAO Lili(
), TIAN Yumei, NING Yanhua, TANG Yuanyuan
Received:2022-05-15
Online:2023-01-10
Published:2022-12-30
摘要:
目的 检索、评价并总结国内外关于大肠癌放化疗患者消化道症状群护理的证据,为临床实践提供循证依据。 方法 根据“6S”模型,系统检索国内外相关数据库和网站中与大肠癌放化疗患者消化道症状群护理有关的文献,包括临床决策、指南、系统评价、证据总结及专家共识,检索时限为2017年1月—2022年4月。2名研究者对纳入文献进行独立评价后整合证据。 结果 共纳入16篇文献,其中临床决策5篇、指南6篇、系统评价3篇、证据总结2篇。从组织管理、便秘护理、腹泻护理、恶心与呕吐护理4个方面汇总了28条证据。 结论 该研究总结了大肠癌放化疗患者消化道症状群护理的最佳证据,可为临床实践提供参考,护理人员应结合患者症状和实际需求提供个体化护理。
杨俊琳, 杨健, 赵丽丽, 田玉梅, 宁艳花, 汤媛媛. 大肠癌放化疗患者消化道症状群护理的证据总结[J]. 中华护理杂志, 2023, 58(1): 98-104.
YANG Junlin, YANG Jian, ZHAO Lili, TIAN Yumei, NING Yanhua, TANG Yuanyuan. Evidence summary for the nursing of gastrointestinal symptom clusters in colorectal cancer patients with chemoradiotherapy[J]. Chinese Journal of Nursing, 2023, 58(1): 98-104.
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表3 大肠癌放化疗患者消化道症状群护理的证据总结
Table 3 Evidence summary for the nursing of gastrointestinal symptom clusters in colorectal cancer patients with chemoradiotherapy
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| [1] |
Sung H, Ferlay J, Siegel RL, et al. Global cancer statistics 2020:GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries[J]. CA Cancer J Clin, 2021, 71(3):209-249.
DOI URL |
| [2] |
Siegel RL, Torre LA, Soerjomataram I, et al. Global patterns and trends in colorectal cancer incidence in young adults[J]. Gut, 2019, 68(12):2179-2185.
DOI PMID |
| [3] | 国家癌症中心中国结直肠癌筛查与早诊早治指南制定专家组. 中国结直肠癌筛查与早诊早治指南(2020,北京)[J]. 中华肿瘤杂志, 2021, 43(1):16-38. |
| Expert Group of the Development of China Guideline for the Screening,Early Detection and Early Treatment of Colorectal Cancer,National Cancer Center. China guideline for the screening,early detection and early treatment of colorectal cancer(2020,Beijing)[J]. Chin J Oncol, 2021, 43(1):16-38. | |
| [4] | National Institute of Clinical Evidence. Colorectal cancer[EB/OL].(2020-01-29)[2021-12-15]. https://www.nice.org.uk/guidance/ng151/colorectalcancer. |
| [5] | 李桂, 聂小菲, 陈晓莉, 等. 结直肠癌患者术后化疗期间的症状群研究[J]. 护理学杂志, 2017, 32(22):15-19. |
| Li G, Nie XF, Chen XL, et al. Symptom clusters in surgically treated colorectal cancer patients undergoing chemotherapy[J]. J Nurs Sci, 2017, 32(22):15-19. | |
| [6] | Walling AM, Weeks JC, Kahn KL, et al. Symptom prevalence in lung and colorectal cancer patients[J]. J Pain Symptom Mana-ge, 2015, 49(2):192-202. |
| [7] |
Sun WP, Dou RX, Chen JH, et al. Impact of long-course neoadjuvant radiation on postoperative low anterior resection syndrome and quality of life in rectal cancer:post hoc analysis of a randomized controlled trial[J]. Ann Surg Oncol, 2019, 26(3):746-755.
DOI URL |
| [8] |
Couwenberg AM, Burbach JPM, et al. Effect of neoadjuvant therapy and rectal surgery on health-related quality of life in patients with rectal cancer during the first 2 years after diagnosis[J]. Clin Colorectal Cancer, 2018, 17(3):e499-e512.
DOI URL |
| [9] | Venkatesan T, Levinthal DJ, Tarbell SE, et al. Guidelines on ma-nagement of cyclic vomiting syndrome in adults by the American Neurogastroenterology and Motility Society and the Cyclic Vomiting Syndrome Association[J]. Neurogastroenterol Motil, 2019, 31(Suppl 2):e13604. |
| [10] |
Muscaritoli M, Arends J, Bachmann P, et al. ESPEN practical guideline:clinical nutrition in cancer[J]. Clin Nutr, 2021, 40(5):2898-2913.
DOI PMID |
| [11] | 胡雁, 郝玉芳. 循证护理学[M]. 2版. 北京: 人民卫生出版社, 2018. |
| Hu Y, Hao YF. Evidence-based nursing[M]. 2nd ed. Beijing: Peopl’s Medical Publishing House, 2018. | |
| [12] |
刘婷, 谭小雪, 徐娜飞, 等. 妊娠期糖尿病孕妇运动方案的最佳证据总结[J]. 中华护理杂志, 2020, 55(10):1514-1519.
DOI |
|
Liu T, Tan XX, Xu NF, et al. Evidence summary of exercise regimens for patients with gestational diabetes mellitus[J]. Chin J Nurs, 2020, 55(10):1514-1519.
DOI |
|
| [13] |
高洪莲, 王春美, 王晓敏, 等. 非药物干预促进胃肠道恶性肿瘤患者术后功能恢复的最佳证据总结[J]. 中华护理杂志, 2022, 57(2):215-222.
DOI |
|
Gao HL, Wang CM, Wang XM, et al. Evidence summary for nonpharmacological interventions in promoting gastrointestinal function recovery after gastrointestinal malignancies surgery[J]. Chin J Nurs, 2022, 57(2):215-222.
DOI |
|
| [14] | Haggstrom DA, Cheung WY, Nekhlyudov L. Approach to the long-term survivor of colorectal cancer[EB/OL].(2022-01-21)[2022-04-30]. https://www.uptodate.cn/zh-Hans/contents/approa-ch-to-the-long-term-survivor-of-colorectal-cancer. |
| [15] | Hesketh PJ. Prevention and treatment of chemotherapy-indu-ced nausea and vomiting in adults[EB/OL].(2022-01-03)[2022-04-30]. https://www.uptodate.cn/zh-Hans/contents/preven-tion-and-treatment-of-chemotherapy-induced-nausea-and-vomiting-in-adults. |
| [16] | Feyer P, Jordan K. Radiotherapy-induced nausea and vomiting:prophylaxis and treatment[EB/OL].(2022-04-05)[2022-04-30]. https://www.uptodate.cn/zh-Hans/contents/zh-Hans/radiotherapy-induced-nausea-and-vomiting-prophylaxis-and-treatment. |
| [17] | Krishnamurthi SS, Macaron C. Management of acute chemothe-rapy-related diarrhea[EB/OL].(2020-10-28)[2022-03-10]. https://www.uptodate.cn/zh-Hans/contents/management-of-acute-chemo-therapy-related-diarrhea. |
| [18] | Wald A, Lamont T, Grover S. Patient education:constipation in adults(beyond the basics)[EB/OL].(2020-07-07)[2022-04-05]. http://www.uptodate.cn/zh-Hans/contents/constipation-in-adults-beyond-the-basics-search. |
| [19] | Benson AB, Venook AP, Al-Hawary MM, et al. Rectal cancer,version 1.2021,NCCN clinical practice guidelines in oncology[EB/OL].(2021-02-25)[2022-04-30]. https://www.nccn.org/gui-delines. |
| [20] |
Benson AB, Venook AP, Al-Hawary MM, et al. Colon cancer,version 2.2021,NCCN clinical practice guidelines in oncology[J]. J Natl Compr Canc Netw, 2021, 19(3):329-359.
DOI URL |
| [21] | 中国医师协会放射肿瘤治疗医师分会, 中华医学会放射肿瘤治疗学分会, 中国抗癌协会肿瘤放射治疗专业委员会, 等. 中国直肠癌放射治疗指南(2020年版)[J]. 国际肿瘤学杂志, 2021, 48(7):389-401. |
| Radiation Oncology Therapeutic Physician Society of Chinese Medical Doctor Association, China Society for Radiation Oncology, Chinese Association of Radiation Therapy, et al. Gui-delines for radiotherapy of rectal cancer in China (2020 edition)[J]. J Int Oncol, 2021, 48(7):389-401. | |
| [22] | Registered Nurses’ Association of Ontario. A proactive approa-ch to bladder and bowel management in adults[M]. 4th ed. Toronto:RNAO, 2020. |
| [23] |
Hesketh PJ, Kris MG, Basch E, et al. Antiemetics:ASCO gui-deline update[J]. J Clin Oncol, 2020, 38(24):2782-2797.
DOI PMID |
| [24] |
Bossi P, Antonuzzo A, Cherny NI, et al. Diarrhoea in adult can-cer patients:ESMO clinical practice guidelines[J]. Ann Oncol, 2018, 29(Suppl 4):iv126-iv142.
DOI URL |
| [25] |
Dikeocha IJ, Al-Kabsi AM, Eid EEM, et al. Probiotics supplementation in patients with colorectal cancer:a systematic re-view of randomized controlled trials[J]. Nutr Rev, 2021, 80(1):22-49.
DOI PMID |
| [26] |
Lin S, Shen YF. The efficacy and safety of probiotics for prevention of chemoradiotherapy-induced diarrhea in people with abdominal and pelvic cancer:a systematic review and Meta-analysis based on 23 randomized studies[J]. Int J Surg, 2020, 84:69-77.
DOI URL |
| [27] | Lawrie TA, Green JT, Beresford M, et al. Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary pelvic cancers[J]. Cochrane Database Syst Rev, 2018, 1:CD012529. |
| [28] | 姚小云, 陈红宇, 胡君娥, 等. 癌症患者化疗相关性便秘评估与管理最佳证据总结[J]. 护理学报, 2020, 27(2):48-52. |
| Yao XY, Chen HY, Hu JE, et al. Summary of the best evidence for evaluation and management of cancer chemotherapy-related constipation[J]. J Nurs China, 2020, 27(2):48-52. | |
| [29] | 丁娟, 刘晁含, 严玉娇, 等. 癌症患者化疗相关性便秘的最佳证据总结[J]. 中华现代护理杂志, 2020, 26(12):1550-1554. |
| Ding J, Liu CH, Yan YJ, et al. Summary of the best evidence for chemotherapy-related constipation in cancer patients[J]. Chin J Mod Nurs, 2020, 26(12):1550-1554. | |
| [30] |
杨雪凝, 李雪儿, 王松, 等. 慢性阻塞性肺疾病患者呼吸肌训练的最佳证据总结[J]. 中华护理杂志, 2022, 57(1):49-55.
DOI |
|
Yang XN, Li XE, Wang S, et al. Summary of best evidence of respiratory muscle training in patients with chronic obstructive pulmonary disease[J]. Chin J Nurs, 2022, 57(1):49-55.
DOI |
|
| [31] |
Badgeley A, Anwar H,Modi, et al. Effect of probiotics and gut microbiota on anti-cancer drugs:mechanistic perspectives[J]. Biochim Biophys Acta Rev Cancer, 2021, 1875(1):188494.
DOI URL |
| [32] |
褚彦香, 王颖, 熊欢. 分级管理方案在乳腺癌患者化疗所致恶心呕吐中的应用[J]. 中华护理杂志, 2019, 54(12):1815-1819.
DOI |
|
Chu YX, Wang Y, Xiong H. Clinical practice of grading management scheme for chemotherapy induced nausea and vomiting in breast cancer patients[J]. Chin J Nurs, 2019, 54(12):1815-1819.
DOI |
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