中华护理杂志 ›› 2020, Vol. 55 ›› Issue (7): 988-993.DOI: 10.3761/j.issn.0254-1769.2020.07.005

• 静脉血栓护理专题 • 上一篇    下一篇

足月妊娠产妇产后静脉血栓栓塞症快速评估简表的构建及预测效果检验

龚文艳,周璇,侯黎莉()   

  1. 200092 上海市 同济大学医学院(龚文艳);上海交通大学医学院附属国际和平妇幼保健院产科(周璇);上海交通大学医学院附属第九人民医院护理部(侯黎莉)
  • 收稿日期:2019-11-23 出版日期:2020-07-15 发布日期:2020-07-16
  • 通讯作者:
  • 作者简介:龚文艳:女,本科(硕士在读),主管护师,护士长,E-mail:1452736330@qq.com
  • 基金资助:
    国际和平妇幼保健院院内基金(YN201906)

Construction and validation of a rapid assessment form for venous thromboembolism in women after full-term delivery

GONG Wenyan,ZHOU Xuan,HOU Lili()   

  • Received:2019-11-23 Online:2020-07-15 Published:2020-07-16

摘要:

目的 探讨足月妊娠产妇产后并发静脉血栓栓塞症(venous thromboembolism,VTE)的危险因素,在此基础上构建足月妊娠产妇产后VTE快速评估简表,并对其预测效果进行验证。 方法 采用回顾性病例对照研究,收集2018年4月—2019年9月在上海市某三级甲等专科医院产科分娩的足月妊娠产后并发VTE的29例产妇和未并发VTE的58例产妇的相关资料,对相关资料进行单因素和多因素分析,确定足月妊娠产妇产后并发VTE的危险因素,并构建足月妊娠产妇产后VTE快速评估简表,对简表区分度和预测效果进行检验。结果 多因素Logistic回归结果显示,年龄、分娩前BMI、妊娠期糖尿病、家族史(血栓、糖尿病、心血管系统疾病)、受孕方式是影响足月妊娠产妇产后并发VTE的独立危险因素(P<0.05)。根据足月妊娠产妇产后VTE快速评估简表进行风险分层,高危组与低危组差异具有统计学意义(P<0.001),ROC曲线下面积为0.757,灵敏度为55.2%、特异度为74.1%。 结论 年龄≥35岁、分娩前BMI≥30、患有妊娠期糖尿病、有相关疾病家族史、接受辅助生殖技术的产妇更易产后并发VTE。足月妊娠产妇产后VTE快速评估简表有良好的区分度,能较好地预测足月妊娠产妇产后并发VTE的风险。

关键词: 足月妊娠产妇, 静脉血栓栓塞症, 危险因素, 风险评估, 产科护理

Abstract:

Objective To explore risk factors of venous thromboembolism(VTE) in full-term delivery women,so as to construct a rapid assessment form of VTE in full-term postpartum women and to test its predictive effects. Methods A retrospective case-control study was conducted to collect 29 cases of full-term postpartum women with VTE from April 2018 to September 2019 in an observation group,and 58 cases of women with delivery time of a week before or after the deliver time of the observation group were selected in a control group. Chi-square test and Logistic regression were conducted to determine the risk factors of VTE in women after full-term delivery,and a rapid assessment form of VTE in full-term postpartum was constructed to analyze the differentiation of the rapid form and the effects of risk prediction. Results Multivariate logistic regression showed that age,BMI before delivery,gestational diabetes mellitus,family history(thrombosis,diabetes,cardiovascular disease)and pregnancy mode were independent risk factors(P<0.05). The difference between high risk group and low risk group was statistically significant(P<0.001). The area under ROC curve was 0.757;the sensitivity was 55.2%;the specificity was 74.1%. Conclusion The age≥35 s,BMI≥30kg/㎡ before delivery,gestational diabetes mellitus,family history of related diseases and assisted reproductive technology are more likely to cause VTE after full-time delivery. The rapid assessment form of VTE in women after full-term delivery has a good differentiation,which can predict the risk of VTE in full-term postpartum women with a certain clinical value for application.

Key words: Full-term Parturient Women, Venous Thromboembolism, Risk Factors, Risk Assessment, Obstetrical Nursing Care