Objective To explore the effects of double subjects health education based on online maternal school combined with teach-back in pregnant women with gestational diabetes mellitus（GDM） and their spouses. Methods Convenient sampling method was adopted to select pregnant women with GDM and their spouses attending the antenatal clinic at a tertiary general hospital in Quanzhou City from January to June 2021. They were randomized into an experimental group（n=65） or a control group（n=65）. The experimental group received online maternal education combined with teach-back method，while their counterparts in the control group were given routine maternal education. Self-management scale，quality of life questionnaire，blood glucose level，positive aspects of caregiver scale，and rate of macrosomia were measured and compared between the 2 groups before and after the intervention. Results After the intervention，the score of self-management scale was（85.22±2.91） in the experimental group，and it was（59.00±3.18） in the control group，and the difference was statistically significant（t=46.851，P<0.001）；the score of quality of life questionnaire was（78.68±3.36） in the experimental group，and it was（48.00±2.58） in the control group，and the difference was statistically significant（t=55.990，P<0.001）. The score of spouse positive aspects of caregiver scale in the experimental group was（42.02±2.89），and（28.77±3.43） in the control group，with statistically significant between the 2 groups（t=-22.779，P<0.001）. The level of fasting blood glucose（t=-15.881，P<0.001），2 h postprandial blood glucose（t=-12.308，P<0.001） and rate of macrosomia in the experimental group were significantly lower than those in the control group（ χ2=5.783，P=0.016）. Conclusion Double subjects health education based on online maternal school combined with teach-back can activate the support of spouse，improve self-management ability and quality of life of pregnant women with GDM，achieve blood glucose control and reduce the rate of macrosomia.
