Objective To retrieve the relevant evidence for the assessment and management of volume load in maintenance hemodialysis （MHD） patients,and to summarize the best evidence,so as to provide evidence-based bases for medical staff to evaluate the volume load of MHD patients. Methods The guideline database and comprehensive database were searched,including WHO Guidelines,NICE,GIN,AHRQ,SIGN,Cochrane Library,BMJ Best Practice,UpToDate,Yimaitong,PubMed,Web of Science,Embase,CINAHL,CNKI,Wanfang,Med Online,CMJD. All the evidence were searched on assessment of volume load in MHD patients,including guidelines,evidence summaries,best practice,systematic evaluations,meta analysis and original research. The retrieval time was from January 2015 to December 2020. The literature was screened and evaluated,in order to summarize the best evidence. Results 11 articles were finally included,including 8 guidelines and 3 systematic reviews（including meta-analysis）. 19 pieces of best evidence were summarized in 7 aspects including volume load assessment methods,dry weight assessment and optimization,blood pressure control and drug use,sodium intake and elimination,diet assessment and fluid restriction,dialysis frequency and time,and the use of bio-impedance equipment. Conclusion In the assessment of volume load in MHD patients,a multidisciplinary assessment method of shared decision making is practical. In clinical practice,medical staff should select the best evidence based on specific clinical situations and patient wishes. In order to improve the accuracy of the assessment of volume load in MHD patients,a scientific,effective,and easy-to-use comprehensive assessment method and capacity management measure is meant to be further studied.
