Abstract:

Objective To retrieve，evaluate and summarize the best evidence for blood glucose monitoring and management in patients with diabetes of the exocrine pancreas（DEP），and to provide evidence-based basis for clinical practice. Methods According to the “6S” evidence model，relevant evidence on blood glucose management in patients with DEP was searched from computer decision support systems，guideline networks，professional association websites and databases from top to bottom，covering clinical decision-making，clinical practice guidelines，evidence summaries，systematic reviews，expert consensuses，and randomized controlled trials. The search scope was from the establishment of the databases to June 30，2024. Totally 2 researchers independently evaluated the quality of the included literature，and extracted data and summarized evidence that met the criteria. Results A total of 10 articles were included，including 3 guidelines，1 expert consensus，2 systematic reviews，1 clinical decision，1 RCT，and 2 cohort studies. Finally，26 pieces of best evidence were formed from 5 aspects，including blood glucose management team construction and goals，blood glucose monitoring methods，glucose control medication management，lifestyle health education and treatment of hypoglycemia. Conclusion This study summarizes the best evidence for blood glucose monitoring and management in DEP patients，which can provide resource preparation for clinical translation and a basis for medical staff to carry out blood glucose management in DEP patients.

Key words: Diabetes of the Exocrine Pancreas, Type 3c Diabetes Mellitus, Blood Glucose Monitoring, Blood Glucose Management, Evidence-Based Nursing, Summary of Evidence

摘要：

目的 检索、评价、汇总胰腺外分泌疾病糖尿病（diabetes of the exocrine pancreas，DEP）患者血糖监测及管理的最佳证据，为开展临床实践提供循证依据。方法 按照“6S”证据模型自上而下检索指南网、专业协会网站和数据库中关于DEP患者血糖监测及管理的相关证据，涵盖临床决策、指南、证据总结、系统评价、专家共识及随机对照试验，检索时限为建库至2024年6月30日。由2名研究者独立对纳入文献的质量进行评价，并进行资料提取与证据汇总。结果 共纳入10篇文献，包括3篇指南、1篇专家共识、2篇系统评价、1篇临床决策、1篇随机对照试验和2篇队列研究。最终从DEP患者血糖管理团队建设与目标、血糖监测方法、控糖用药管理、生活方式健康教育及低血糖的处理5个方面形成了26条最佳证据。结论 该研究总结了DEP患者血糖监测及管理的最佳证据，可为临床转化提供资源准备，为医护人员进行DEP血糖管理提供依据。

关键词: 胰腺外分泌疾病糖尿病, 3c型糖尿病, 血糖监测, 血糖管理, 循证护理学, 证据总结