Abstract:

Objective To systematically evaluate the psychometric properties of specific self-reported outcome assessment tools for patients undergoing Endoscopic Transnasal Transsphenoidal Surgery（ETTS），with the aim of pro-viding clinical healthcare professionals with evidence to guide the selection of appropriate assessment tools. Methods A systematic search was performed across multiple databases，including the North American Skull Base Society，PubMed，Embase，CINAHL，Web of Science，Cochrane Library，CNKI，VIP database，Wanfang database，and the China Biomedical Literature Database，for studies published from the inception of each database to January 9，2025，that are related to ETTS-specific symptom assessment tools. Totally 2 independent researchers screened the literature and extracted relevant data. The consensus-based health measurement tool selection bias risk checklist and quality standards were used to evaluate the methodological quality and psychometric properties of the included studies，which helped to form the development of recommendations. Results A total of 11 articles were included，covering 8 specific self-reported outcome assessment tools for patients undergoing endonasal transsphenoidal pituitary tumor resection. Of these，the Pituitary Outcome Score and the Leiden Bother and Needs Questionnaire for patients with pituitary disease 2 tools were rated as Grade A recommendations，and 6 tools were rated as Grade B recommendations. Conclusion POS and LBNQ-Pituitary are recommended due to their relatively strong overall methodological quality and psychometric properties. However，further validation with larger sample sizes is necessary.

Key words: Pituitary Tumor, Surgery, Self-Reported Outcome, Assessment Tools, Measurement Properties, Systematic Review, Evidence-Based Nursing

摘要：

目的 对经鼻蝶垂体瘤手术（endoscopic transnasal transsphenoidal surgery，ETTS）患者的特异性自我报告结局评估工具的测量学属性进行系统评价，以期为临床医护人员选择合适的评估工具提供依据。方法 系统检索北美颅底学会、PubMed、Embase、CINAHL、Web of Science、Cochrane Library、中国知网、维普数据库、万方数据库及中国生物医学文献数据库中公开发表的与ETTS患者特异性症状评估工具相关的研究，检索时限为建库至2025年1月9日，由2名研究者独立筛选文献、资料提取，采用基于共识的健康测量工具遴选标准偏倚风险清单及其质量标准，评定纳入研究的方法学质量及测量学属性，并形成推荐意见。结果 共纳入11项研究，涉及8个ETTS患者特异性自我报告结局评估工具。其中，垂体结局评分和垂体疾病患者困扰与需求问卷为A级推荐，其他6个为B级推荐。结论 推荐使用垂体结局评分和垂体疾病患者困扰与需求问卷，其总体方法学质量及测量学属性相对较好，但仍需进一步大样本验证。

关键词: 垂体瘤, 手术, 自我报告结局, 评估工具, 测量学属性, 系统评价, 循证护理学