Abstract:

Objective To evaluate the effect of remote interventions with digital health technologies in lung transplant patients. Methods Databases，including CKNI，Wangfang，VIP，CMB，Cochrane Library，PubMed，Embase，Web of Science，Scopus and BMJ Best Practice were searched from their inception to July 2023. There were 2 researchers who independently screened and extracted the literature，and then evaluated quality of the included studies. Meta-analysis was performed using RevMan 5.2. Results 10 studies with 1 262 patients were included. The results of meta-analysis showed that compared with conventional intervention，remote intervention based on digital health technology could improve self-monitoring compliance of lung transplant patients[OR=0.64，95%CI（0.46，0.88），P=0.006]，improve quality of life including mental health status[OR=3.08，95%CI（0.41，5.74），P=0.020] and physical health status[OR=3.81，95%CI（1.19，6.43），P=0.004]. In terms of the intervention forms，the application-based remote intervention had better self-monitoring compliance，and the difference was statistically significant（P=0.007）. However，in terms of the comparison of readmission rate[OR=1.73，95%CI（0.98，3.04），P=0.060]，anxiety[OR=-0.12， 95%CI（-1.36，1.11），P=0.850]，and depression[OR=0.62，95%CI（-0.80，2.03），P=0.390]，the effect of intervention was unclear. Conclusion Remote intervention based on digital health technology can improve self-monitoring compliance and quality of life in lung transplant patients；applications are the optimal form of intervention. Limited by the quality and quantity of included studies and the heterogeneity of study results，more high-quality studies are needed to further verify the effects of digital health technology on readmission rates，anxiety and depression of lung transplant patients.

Key words: Digital Health Technology, Lung Transplantation, Self-Monitoring Compliance, Remote Inter-vention, Meta-Analysis, Evidence-Based Nursing

摘要：

目的 评价基于数字健康技术的远程干预在肺移植患者中的应用效果。方法 计算机检索中国知网、万方数据库、维普数据库、中国生物医学文献数据库、Cochrane Library、PubMed、Embase、Web of Science、Scopus和 BMJ Best Practice，检索时限为建库至2023年7月。由2名研究者独立检索并筛选文献，进行文献质量评价后，采用RevMan 5.2 软件进行Meta分析。结果 共纳入10篇文献，总计1 262例患者。Meta分析结果显示，与常规干预相比，基于数字健康技术的远程干预能提高肺移植患者自我监测依从性[OR=0.64，95%CI（0.46，0.88），P=0.006]、改善生活质量，包括心理健康状态[OR=3.08，95%CI（0.41，5.74），P=0.020]和生理健康状态[OR=3.81，95%CI（1.19，6.43），P=0.004]；干预形式中，基于应用程序的远程干预，患者自我监测依从性更好，差异具有统计学意义（P=0.007）；但再入院率[OR=1.73，95%CI（0.98，3.04），P=0.060]、焦虑[OR=-0.12，95%CI（-1.36，1.11），P=0.850]、抑郁[OR=0.62，95%CI（-0.80，2.03），P=0.390]等方面比较，干预效果尚不明确。结论 基于数字健康技术的远程干预能提高肺移植患者自我监测依从性、改善生活质量；应用程序是最优的干预形式。受纳入研究质量、数量以及研究结果异质性的限制，仍需更多高质量研究进一步验证数字健康技术对肺移植患者再入院率、焦虑、抑郁的影响。

关键词: 数字健康, 肺移植, 自我监测依从性, 远程干预, Meta分析, 循证护理学