Abstract:

Objective To explore the effects of improvement in timing of medication administration in patients with pain after liver cancer embolization.Methods A total of 160 patients underwent liver cancer embolization were divided into the intervention group and the control group according to random number table method with 80 cases in each group. In the intervention group,the daily medication administration time was set at 15：00 and 21：00,the time was set at 9：00 and 15：00 for the control group. The incidence of pain occurred in different time periods within 24 hours and pain control satisfaction after liver cancer embolization were recorded.Results Incidence of pain decreased in the intervention group（P<0.05）,satisfaction of pain control was significantly improved in the intervention group（P<0.05）.Conclusion Improvement in timing of medication administration is helpful for pain management in patients after liver cancer embolization.

Key words: Liver Neoplasms, Embolization, Therapeutic, Pain, Postoperative, Drug Chronotherapy

摘要：

目的 探讨择时给药时间点的改进在肝癌栓塞术后疼痛患者中的应用效果。方法 将160例肝癌栓塞术后患者,按随机数字表法分为试验组80例和对照组80例。试验组每日给药时间为15：00和21：00;对照组每日给药时间为09：00和15：00。记录用药后24 h内不同时段的疼痛强度,及疼痛控制满意度。结果 应用择时给药时间点后,患者的疼痛强度下降（P<0.05）;患者疼痛控制满意度明显提高（P<0.05）。结论按择时给药时间点给药,有助于肝栓塞术后患者疼痛管理。

关键词: 肝肿瘤, 栓塞, 治疗性, 疼痛, 手术后, 药物时间疗法