Abstract:

Objective The development of the expert consensus on self-management of skin adverse reactions in patients undergoing targeted cancer therapy（hereinafter referred to as “the consensus”） aims to enhance the effectiveness of self-management for skin-related adverse reactions in cancer patients receiving targeted therapy. It seeks to reduce the incidence of these reactions and alleviate their severity. Methods Utilizing evidence-based approaches，a systematic search was conducted across both domestic and international databases and relevant websites. This process included the evaluation and summarization of pertinent evidence to create a preliminary draft of the consensus. Through 2 rounds of Delphi expert inquiries and a round of expert panel discussion，the content was refined，leading to the final draft of the consensus. Results The consensus comprises 11 sections：gathering information before medication，identifying risk factors prior to medication，self-assessment and proactive reporting，skin cleansing，skin moisturizing，sun protection，makeup application，appropriate clothing，engaging in household activities，prophylactic medication，and common management techniques. Conclusion This consensus provides a valuable reference for clinical nurses to guide cancer patients in the self-management of skin adverse reactions associated with targeted drug therapy.

Key words: Oncologic Nursing, Targeted Therapy, Self-Management, Cutaneous Adverse Reaction, Expert Consensus

摘要：

目的 制订肿瘤靶向药物治疗相关皮肤不良反应患者自我管理的专家共识（以下简称“共识”），为提高肿瘤患者在应用靶向药物治疗时针对相关皮肤不良反应进行有效的自我管理、降低皮肤不良反应的发生率及减轻其严重程度提供参考。方法 以循证方法为指导、临床需求为导向，系统检索国内外数据库及相关网站；评价和汇总相关证据，形成“共识”初稿；通过2轮专家函询和1轮专家论证会，对内容进行调整并达成共识，形成“共识”终稿。结果 “共识”包括用药前信息获取、用药前风险因素识别、自我评估及主动报告、皮肤清洁、皮肤保湿、防晒、化妆、穿戴、家务活动、药物预防、常见处理方法共11个部分。结论 该“共识”可为临床护士指导肿瘤患者开展靶向药物治疗相关皮肤不良反应的自我管理提供参考。

关键词: 肿瘤护理, 靶向治疗, 自我管理, 皮肤不良反应, 专家共识