肺癌患者化疗期间症状群的范围综述

doi:10.3761/j.issn.0254-1769.2024.18.015

摘要/Abstract

摘要：

目的对肺癌患者化疗期间症状群相关研究进行范围综述，明确症状群种类、评估工具及化疗期间的变化特点，为今后开展肺癌患者症状群研究提供参考。方法以澳大利亚乔安娜布里斯研究所循证卫生保健中心范围综述指南为方法学框架，检索PubMed、Embase、CINAHL、Web of Science、Scopus、中国知网、万方数据库及中国生物医学文献数据库中关于肺癌患者化疗期间症状群的研究。检索时限为建库至2023年12月31日。对纳入文献进行数据提取及汇总分析。结果共纳入19篇文献，提取出22个症状群，主要包括心理症状群、胃肠道症状群、肺癌特异性症状群、疲乏相关症状群和呼吸道相关症状群等；症状群评估工具共6种，其中4种为不同版的安德森症状评估量表；化疗前肺癌特异性和心理症状群最严重，第1次化疗后胃肠道症状群最严重，化疗间歇期疲乏相关症状群最严重，第3次化疗后无核心症状群。结论肺癌患者化疗期间存在多种症状群，症状群的命名及症状归属有待进一步规范，肺癌化疗患者症状群的评估工具以安德森症状评估量表及其他语言版为主，肺癌患者化疗期间症状群呈动态变化，不同阶段核心症状群存在差异。

关键词: 症状群, 肺癌, 化疗, 范围综述, 护理

Abstract:

Objective To identify the characteristics and research status of symptom clusters in patients with lung cancer patients during chemotherapy. Methods This scoping review was conducted under the Joanna Briggs Institute guidelines. A literature search was performed in the PubMed，Embase，CINAHL，Web of Science，Scopus，CNKI，Wanfang，and CBM databases to identify relevant studies about symptom clusters in patients with lung cancer from inception until December 31，2023. The included studies were summarized and analyzed. Results 19 papers were included and 22 symptom clusters were extracted，mainly including psychological，gastrointestinal，lung cancer-specific，fatigue-related，and respiratory symptom clusters. There are 6 symptom cluster assessment tools，of which 4 were M.D Anderson Symptom Inventory in different version；the symptom clusters were dynamically changing during chemotherapy in patients with lung cancer，with variations in core symptom clusters at different stages. Conclusion Multiple symptom clusters exist during chemotherapy in lung cancer patients，and the naming of symptom clusters and attribution of symptoms need to be further standardized. The assessment tools for symptom clusters in patients undergoing chemotherapy for lung cancer are mainly based on the Anderson Symptom Assessment Scale and other language versions. Symptom clusters in patients with lung cancer during chemotherapy show dynamic changes，and there are differences in core symptom groups at different stages.

Key words: Symptom Cluster, Lung Neoplasms, Chemotherapy, Scoping Review, Nursing Care

李芙兰, 谢海霞, 于天爽, 汉瑞娟. 肺癌患者化疗期间症状群的范围综述[J]. 中华护理杂志, 2024, 59(18): 2283-2289.

LI Fulan, XIE Haixia, YU Tianshuang, HAN Ruijuan. Symptom clusters in patients with lung cancer patients during chemotherapy：a scoping review[J]. Chinese Journal of Nursing, 2024, 59(18): 2283-2289.

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