HIV感染者合并慢性非传染性疾病多药依从性管理的研究进展

doi:10.3761/j.issn.0254-1769.2022.14.019

摘要/Abstract

摘要：

由于艾滋病抗病毒药物的广泛使用,HIV感染者寿命得以延长,老年HIV感染者的人数不断增多,最终导致HIV合并慢性非传染性疾病（chronic non-communicable diseases,NCDs）的人群逐年递增。NCDs包括心血管疾病、糖尿病、癌症和慢性呼吸道疾病等,需要长期服用多种药物,加之复杂的HIV抗病毒药物方案,会导致HIV感染者服药依从性降低,出现错服、漏服等现象。HIV感染者多药依从性问题逐渐引起重视。该文系统回顾了HIV感染者合并NCDs多药依从性管理的相关研究,对HIV感染者合并NCDs多药依从性的定义和影响因素进行阐述,并提出提高合并NCDs的HIV感染者多药依从性的干预措施,以期为HIV感染者多药依从性管理的研究和护理实践提供参考。

关键词: HIV感染, 慢性非传染性疾病, 多种药物疗法, 依从性, 护理

Abstract:

Due to the widespread use of AIDS antiretroviral drugs,the life expectancy of people infected with the human immunodeficiency virus（HIV） has been prolonged. The number of elderly people living with HIV has been increasing and eventually leading to the increase of HIV-infected people with chronic non-communicable diseases （NCDs） year by year. NCDs,including cardiovascular diseases,diabetes,cancer and chronic respiratory disease,require long-term use of multiple medications（polypharmacy） and complex antiretroviral drug regimens,which may lead to the reduced compliance of HIV-infected patients with medication,such as medication errors or missed medication. The problem of polypharmacy adherence of HIV-infected patients has gradually attracted people’s attention. This article systematically reviewed the related studies on the management of polypharmacy adherence in HIV-infected patients with NCDs,elaborated the definition and influencing factors of polypharmacy adherence,and proposed intervention measures to improve the polypharmacy adherence in HIV-infected patients with NCDs. This article aims to provide a reference for further research on adherence management and nursing practice of HIV-infected persons.

Key words: HIV Infections, Chronic Non-Communicable Diseases, Polypharmacy, Adherence, Nursing Care

何加敏, 朱政, 卢洪洲. HIV感染者合并慢性非传染性疾病多药依从性管理的研究进展[J]. 中华护理杂志, 2022, 57(14): 1788-1793.

HE Jiamin, ZHU Zheng, LU Hongzhou. Research progress on polypharmacy adherence management in HIV-infected people with chronic non-communicable diseases[J]. Chinese Journal of Nursing, 2022, 57(14): 1788-1793.

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