关键词: 白血病, 鞘内注射, 并发症, 平卧, 舒适度, 儿科护理学

Abstract: Objective To explore the effects of different lengths of supine position after intrathecal chemotherapy on occurrence of complications in children with leukemia,in order to determine an optimum length of supine position for improving comfort. Methods Clinical experimental design was adopted, and children patients were assigned into 3 groups according to the sequence of admission using random table number, including supine position for 2 hours,3 hours,and 4 hours after intrathecal chemotherapy. Complications that occurred during supine position and 1 week after intrathecal chemotherapy were recorded. The level of tolerance and activities during supine position were also recorded. Results Totally 180 children were included in this study with 60 cases in each group. There was no significant difference in the incidence of complications among three groups during supine position and in the following week(P>0.05). Difference in the level of tolerance among groups had significant difference (P<0.05)，and the 2-hour group had the best tolerance. There was no difference in activities during supine position among three groups(P>0.05). More physiological needs were observed for longer length of supine position. Conclusion Two hours for supine position after intrathecal chemotherapy does not increase the incidence of complications in children with leukemia, and the level of tolerance would also be improved, which would be recommended.

Key words: Leukemia, Intrathecal Injection, Complication, Supine Positon, Comfort Degree, Pediatric Nursing