集束化营养干预对老年胃癌化疗患者影响的研究

doi:10.3761/j.issn.0254-1769.2020.03.001

摘要/Abstract

摘要：

目的探讨集束化营养干预对老年胃癌化疗患者营养状况及生活质量的影响。方法对348例符合纳入标准并获知情同意的老年胃癌化疗患者采用营养风险筛查2002进行营养风险筛查。有营养风险的186例患者被随机分为试验组（94例）和对照组（92例）,试验组接受集束化营养干预,对照组接受常规营养管理和饮食指导。比较两组干预前后的体重、体重指数、握力、瘦体重、体脂、体脂百分比、营养摄入量和生活质量。结果老年胃癌化疗患者的营养风险发生率为53%。干预后,试验组体重、体重指数、握力、体脂百分比、瘦体重、75%能量摄入达标率和75%蛋白质摄入达标率均高于对照组,差异有统计学意义（P<0.05）;生活质量评分中试验组的躯体功能、角色功能、情绪功能和整体健康评分均显著高于对照组,差异有统计学意义（P<0.05）;而疲劳、恶心呕吐、食欲下降和失眠评分均显著低于对照组,差异有统计学意义（P<0.05）。结论集束化营养干预可显著改善老年胃癌化疗患者的营养状况,降低患者营养不良的发生率,提高患者的生活质量。

关键词: 胃肿瘤, 营养不良, 营养支持, 集束化营养干预, 老年人, 住院患者, 营养状况, 生活质量

Abstract:

Objective To explore the effects of bundle nutrition intervention on improving the nutritional status and quality of life among elderly patients with gastric cancer undergoing chemotherapy. Methods A total of 348 elderly patients with gastric cancer who met the inclusion criteria and received informed consent were enrolled and received nutritional risk screening using nutritional risk screening 2002（NRS-2002）. Totally 186 patients with nutritional risk were randomly allocated into the experimental group（94 cases） and the control group（92 cases）. The experimental group received bundle nutritional intervention. The control group received routine nutrition management and dietary guidance. The body weight,body mass index（BMI）,grip strength,lean body mass,body fat,body fat percentage,nutritional intake and quality of life were compared between 2 groups before and after the intervention. Results The prevalence of nutritional risk was 53%. After intervention,the body weight,BMI,grip strength,body fat percentage,lean body mass,75% energy intake and 75% protein intake of the experimental group were higher than those of the control group（P<0.05）. The of physical function,role function,emotional function and overall health of the experimental group were significantly higher than those of the control group（P<0.05）. The scores of fatigue,nausea and vomiting,loss of appetite and insomnia were significantly lower than those of the control group（P<0.05）. Conclusion Bundle nutrition intervention can significantly improve the nutritional status,decrease the prevalence of malnutrition,and improve the quality of life among elderly patients with gastric cancer undergoing chemotherapy.

Key words: Stomach Neoplasms, Malnutrition, Nutritional Support, Bundle Nutritional Intervention, Elderly People, Inpatient, Nutritional Status, Quality of Life

刘晓萱, 李薇, 霍晓鹏, 于康. 集束化营养干预对老年胃癌化疗患者影响的研究[J]. 中华护理杂志, 2020, 55(3): 325-330.

LIU Xiaoxuan, LI Wei, HUO Xiaopeng, YU Kang. Effects of bundle nutrition intervention on nutritional status and quality of life among elderly patients with gastric cancer undergoing chemotherapy[J]. Chinese Journal of Nursing, 2020, 55(3): 325-330.

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