Centrality and serverity of symptoms in people living with HIV: a cross-sectional study
Objective To explore the prevalence and severity of HIV-related symptoms and to identify symptom networks in people living with HIV（PLWH）.Methods From June to October 2020,we recruited 572 PLWH through a convenient sampling in one HIV/AIDS designated hospital in Kunming,Yunnan Province. HIV Symptom Checklist was used to measure the prevalence and severity of 27 HIV-related symptoms. Spearman association network and Fruchterman-Reingold layout were used to identify symptom networks.Results The most common symptom was fatigue（44.41%）,sleeping disturbance（37.76%）,and memory loss（37.41%）. The most severe symptom was fatigue,sleeping disturbance,and memory loss. The network showed fatigue（rS=8.62,rC=1.16,rB=36） and slow reaction（rS=8.54,rC=1.07,rB=14） were the most central symptoms across three centrality indices including strength,closeness,and betweenness.Conclusion This study suggested that it is particularly important to include assessment and treatment of fatigue and cognitive symptoms as essential components of HIV care. There is a need to evaluate HIV-related symptoms by a structural patient reported outcome measures.
Hongli YANG , Zheng ZHU , Yan HU , Xiongfeng BI , Jinjie XU , Lan LUO , Lin ZHANG . Centrality and serverity of symptoms in people living with HIV: a cross-sectional study[J]. Chinese Journal of Nursing, 2021 , 56(5) : 727 -731 . DOI: 10.3761/j.issn.0254-1769.2021.05.014
| [1] | 卢洪洲. 实用艾滋病护理[M]. 上海: 上海科学技术出版社, 2014. |
| [1] | Lu HZ. Practical AIDS care[M]. Shanghai: Shanghai Scientific & Technical Publishers, 2014. |
| [2] | 朱政, 胡雁, 赵蕊, 等. 艾滋病定点诊疗模式下症状管理的质性研究[J]. 中华护理杂志, 2019,54(5):658-663. |
| [2] | Zhu Z, Hu Y, Zhao R, et al. Current situation of symptom management under the HIV/AIDS designated hospital system:a qualitative research[J]. Chin J Nurs, 2019,54(5):658-663. |
| [3] | Zhu Z, Hu Y, Guo M, et al. Urban and rural differences:unmet needs for symptom management in people living with HIV in China[J]. J Assoc Nurses AIDS Care, 2019,30(2):206-217. |
| [4] | Wilson NL, Azuero A, Vance DE, et al. Identifying symptom patterns in people living with HIV disease[J]. J Assoc Nurses AIDS Care, 2016,27(2):121-132. |
| [5] | Zhu Z, Hu Y, Xing W, et al. Identifying symptom clusters among people living with HIV on antiretroviral therapy in China:a network analysis[J]. J Pain Symptom Manage, 2019,57(3):617-626. |
| [6] | Gajdo? P, Je?owicz T, Uher V, et al. A parallel Fruchterman-Reingold algorithm optimized for fast visualization of large graphs and swarms of data[J]. Swarm Evol Comput, 2016,26:56-63. |
| [7] | Bader DA, Madduri K. Parallel algorithms for evaluating centrality indices in real-world networks[C] //2006 International Con-ference on Parallel Processing(ICPP’06). IEEE, 2006: 539-550. |
| [8] | Bergamaschi A, d’Arripe-Longueville F, Gray LL, et al. Perceived HIV-related physical fatigue,sociodemographic characteristics and physical activity:a cross-sectional study[J]. J Clin Nurs, 2019,28(11/12):2147-2156. |
| [9] | Gebreyesus T, Belay A, Berhe G, et al. Burden of fatigue among adults living with HIV/AIDS attending antiretroviral therapy in Ethiopia[J]. BMC Infect Dis, 2020,20(1):280. |
| [10] | Baye M, Fisseha B, Bayisa M, et al. Experience of fatigue and associated factors among adult people living with HIV attending ART clinic:a hospital-based cross-sectional study in Ethiopia[J]. BMJ Open, 2020,10(10):e042029. |
| [11] | Makic MB, Gilbert D, Jankowski C, et al. Sensor and survey measures associated with daily fatigue in HIV:findings from a mixed-method study[J]. J Assoc Nurses AIDS Care, 2020,31(1):12-24. |
| [12] | Loades ME, Kagee A. Exploring our understanding of fatigue among adolescents living with HIV:highlighting the unknown[J]. J Health Psychol, 2019,24(1):125-136. |
| [13] | Ding Y, Lin H, Liu X, et al. Higher prevalence of frailty among a sample of HIV-infected middle-aged and older Chinese adults is associated with neurocognitive impairment and depressive symptoms[J]. J Infect Dis, 2017,215(5):687-692. |
| [14] | Cohen RA, Seider TR, Navia B. HIV effects on age-associated neurocognitive dysfunction:premature cognitive aging or neurodegenerative disease?[J]. Alzheimers Res Ther, 2015,7(1):37. |
| [15] | Heaton RK, Franklin DR, Ellis RJ, et al. HIV-associated neurocognitive disorders before and during the era of combination antiretroviral therapy:differences in rates,nature,and predictors[J]. J Neurovirol, 2011,17(1):3-16. |
| [16] | de Vaughn S, Müller-Oehring EM, Markey B, et al. Aging with HIV-1 infection:motor functions,cognition,and attention:a comparison with Parkinson’s disease[J]. Neuropsychol Rev, 2015,25(4):424-438. |
| [17] | Wixted J, Serences J. Stevens’ handbook of experimental psychology and cognitive neuroscience,sensation,perception,and attention[M]. New York:John Wiley & Sons, 2018. |
| [18] | Watkins CC, Treisman GJ. Cognitive impairment in patients with AIDS-prevalence and severity[J]. HIV AIDS(Auckl), 2015,7:35-47. |
| [19] | Harezlak J, Buchthal S, Taylor M, et al. Persistence of HIV-associated cognitive impairment,inflammation,and neuronal injury in era of highly active antiretroviral treatment[J]. AIDS, 2011,25(5):625-633. |
| [20] | Kall M, Marcellin F, Harding R, et al. Patient-reported outcomes to enhance person-centred HIV care[J]. Lancet HIV, 2020,7(1):e59-e68. |
| [21] | 皋文君, 袁长蓉. 患者自我报告结局测量信息系统在国外的应用进展[J]. 中华护理杂志, 2018,53(11):1401-1405. |
| [21] | Gao WJ, Yuan CR. The application of patient reported outcomes measurement information system:a literature review[J]. Chin J Nurs, 2018,53(11):1401-1405. |
| [22] | Bristowe K, Clift P, James R, et al. Towards person-centred care for people living with HIV:what core outcomes matter,and how might we assess them? A cross-national multi-centre qualitative study with key stakeholders[J]. HIV Med, 2019,20(8):542-554. |
| [23] | 廖敏, 唐杰, 王冬华. HIV感染者和AIDS患者病耻感的研究进展[J]. 中华护理杂志, 2019,54(4):619-623. |
| [23] | Liao M, Tang J, Wang DH. Stigma in the HIV/AIDS epidemic:a review of the literature[J]. Chin J Nurs, 2019,54(4):619-623. |
| [24] | Calvert M, Kyte D, Price G, et al. Maximising the impact of patient reported outcome assessment for patients and society[J]. BMJ, 2019,364:k5267. |
| [25] | Ishaque S, Karnon J, Chen G, et al. A systematic review of randomised controlled trials evaluating the use of patient-reported outcome measures(PROMs)[J]. Qual Life Res, 2019,28(3):567-592. |
/
| 〈 |
|
〉 |