Abstract:

Objective To evaluate the effectiveness of exercise for people with Parkinson’s disease on sleep quality. Methods Computerized retrieval of PubMed，Web of Science，Embase，the Cochrane Library，CINAHL，CNKI，WanFang Data，VIP，CBM was conducted to collect randomized controlled trials about the effect of exercise on people with Parkinson’s disease from inception to December，2022. There were 2 researchers who independently screened the literature，extracted the data and evaluated the risks of bias in the included studies. Meta-analysis was performed using RevMan 5.4 software. Results A total of 13 studies were included，with 874 patients. The result of meta-analysis show that the overall effect size of exercise intervention on sleep quality for people with Parkinson’s disease is significant(SMD=-0.54，95%CI=[-0.90，-0.19]，P<0.01). Subgroup analysis show that the maximum effect size of intervention frequency is 4-5 times/week（SMD=-0.75）；the maximum effect size of exercise intensity is light intensity（SMD=-2.19）；the maximum effect size of a single intervention time is 40-55 minutes（SMD=-0.69）；the maximum effect size of exercise type is traditional Chinese exercise（SMD=-0.63）；the maximum effect size of intervention cycle is 12 weeks（SMD=-0.66）. Conclusion Exercise intervention has significantly effects to improve sleep quality on Parkinson’s disease patients. It is a more effective way to improve sleep quality by exercising 4-5 times per week，while each exercise lasts about 40-55 min for 12 weeks in Traditional Chinese Medicine exercise with light intensity.

Key words: Exercise, Sleep Quality, Parkinson Disease, Meta-Analysis, Evidence-Based Nursing

摘要：

目的 评价运动锻炼对帕金森病患者睡眠质量影响的干预效果。 方法 计算机检索PubMed、Web of Science、Embase、Cochrane Library、CINAHL、中国知网、万方数据库、维普数据库、中国生物医学文献数据库中关于运动干预帕金森病患者睡眠质量的随机对照试验，检索时限为建库至2022年12月。由2名研究者独立筛选文献、提取资料、评价纳入研究的偏倚风险后，采用RevMan 5.4软件进行统计分析。 结果 共纳入文献13篇，总计874例帕金森病患者，Meta分析结果显示，运动锻炼能够改善帕金森病患者的睡眠质量（SMD=-0.54，95%CI=[-0.90，-0.19]，P<0.01），亚组分析显示，干预频率最大效应量为4~5次/周（SMD=-0.75），运动强度最大效应量为轻度（SMD=-2.19），单次干预时间最大效应量为40~55 min（SMD=-0.69），运动类型最大效应量为中医传统健身运动（SMD=-0.63），干预周期最大效应量为12周（SMD=-0.66）。 结论 运动干预能够改善帕金森病患者的睡眠质量，轻度的中医传统健身运动且单次运动时间为40~55 min，持续时间为12周，干预频率为4~5次/周的运动干预方案改善睡眠质量的效果更好。

关键词: 锻炼, 睡眠质量, 帕金森病, Meta分析, 循证护理学