Research progress on health related quality of life in adult ICU discharged patients

doi:10.3761/j.issn.0254-1769.2021.01.025

Abstract

Abstract:

This article reviews the latest studies on health related quality of life（HRQOL） in adult ICU discharged patients,including the short- and long-term status quo of HRQOL,influencing factors,and interventions. At present,the short- and long-term HRQOL in adult ICU discharged patients still remains unsatisfactory,as there are many influencing factors of HRQOL and the great individual differences of ICU discharged patients. It is suggested that personalized nursing interventions should be carried out in clinical practice aiming at the influencing factors,and effective interventions should be further explored to improve HRQOL of adult ICU discharged patients,so as to provide bases for the construction of systematic intervention plans.

Key words: Intensive Care Units, Health Related Quality of Life, Influencing Factors, Post-Intensive Care Syndrome, Review, Nursing Care

摘要：

对成人ICU转出患者健康相关生活质量（health related quality of life,HRQOL）的研究现状进行综述,包括成人ICU转出患者近期和远期HRQOL的现状、HRQOL的影响因素及干预措施。目前成人ICU转出患者近期和远期HRQOL仍不理想,由于HRQOL的影响因素较多、ICU转出患者的个体差异较大,建议在临床工作中开展针对影响因素的个性化护理干预,进一步探索有效改善ICU转出患者HRQOL的干预方法,为构建系统化干预方案提供依据。

HE Manman,JIANG Zhixia,WANG Ying,HU Rujun,LI Xiaojuan,HE Min,WANG Yu,CHEN Minzhu. Research progress on health related quality of life in adult ICU discharged patients[J]. Chinese Journal of Nursing, 2021, 56(1): 148-154.

何曼曼,江智霞,王颖,胡汝均,李晓娟,何敏,王雨,陈泯竹. 成人ICU转出患者健康相关生活质量的研究进展[J]. 中华护理杂志, 2021, 56(1): 148-154.

References 49

[1]	韦秀霞, 张秀伟, 彭剑英, 等. 国外ICU后综合征的研究现状[J]. 中华护理杂志, 2016,51(1):84-89.
	Wei XX, Zhang XW, Peng JY, et al. Current research status on post-intensive care syndrome[J]. Chin J Nurs, 2016,51(1):84-89.
[2]	Karimi M, Brazier J. Health,health-related quality of life,and quality of life:what is the difference?[J]. Pharmaco economics, 2016,34(7):645-649. DOI URL
[3]	李若祎, 应巧燕, 刘桂英, 等. 院内及院外功能锻炼对ICU后综合征患者影响的研究进展[J]. 中华护理杂志, 2018,53(11):1328-1332.
	Li RY, Ying QY, Liu GY, et al. Research process of functional exercise in and out of hospital for post-intensive care syndrome[J]. Chin J Nurs, 2018,53(11):1328-1332.
[4]	Langerud AK, Rustøen T, Småstuen MC, et al. Health-related quality of life in intensive care survivors:associations with social support,comorbidity,and pain interference[J]. PLoS One, 2018,13(6):e0199656. DOI URL PMID
[5]	Niittyvuopio M, Liisanantti JH, Pikkupeura J, et al. Factors associated with impaired physical functioning and mental health in working-age patients attending a post-intensive care follow-up clinic three months after hospital discharge[J]. Anaesth Intensive Care, 2019,47(2):160-168. DOI URL PMID
[6]	Serviá GL, Badia CM, Montserrat ON, et al. Risk factors for the deterioration of quality of life in critical trauma patients. Assessment at 6 and 12 months after discharge from the intensive care unit[J]. Med Intensiva, 2014,38(1):1-10. DOI URL PMID
[7]	姚丽, 李镜, 丁楠楠, 等. ICU患者出院后生活质量的调查分析[J]. 护理学杂志, 2019,34(15):89-91.
	Yao L, Li J, Ding NN, et al. Investigation on quality of life of ICU patients after discharge[J]. J Nurs Sci, 2019,34(15):89-91.
[8]	Honselmann KC, Buthut F, Heuwer B, et al. Long-term mortality and quality of life in intensive care patients treated for pneumonia and/or sepsis[J]. J Crit Care, 2015,30(4):721-726. DOI URL PMID
[9]	Bastian K, Hollinger A, Mebazaa A, et al. Association of social deprivation with 1-year outcome of ICU survivors:results from the FROG-ICU study[J]. Intensive Care Med, 2018,44(12):2025-2037. DOI URL PMID
[10]	Das Neves AV, Vasquez DN, Loudet CI, et al. Symptom burden and health-related quality of life among intensive care unit survivors in Argentina:a prospective cohort study[J]. J Crit Care, 2015,30(5):1049-1054. DOI URL PMID
[11]	Gerth AMJ, Hatch RA, Young JD, et al. Changes in health-related quality of life after discharge from an intensive care unit:a systematic review[J]. Anaesthesia, 2019,74(1):100-108. DOI URL PMID
[12]	Stergiannis P, Katsoulas T, Fildissis G, et al. Health-related qua-lity of life and rehabilitation cost following intensive care unit stay in multiple trauma patients[J]. J Trauma Nurs, 2014,21(3):115-121. DOI URL PMID
[13]	Orwelius L, Nordlund A, Edell-Gustafsson U, et al. Role of pree-xisting disease in patients’ perceptions of health-related quality of life after intensive care[J]. Crit Care Med, 2005,33(7):1557-1564. DOI URL PMID
[14]	Orwelius L, Nordlund A, Nordlund P, et al. Pre-existing disease:the most important factor for health related quality of life long-term after critical illness:a prospective,longitudinal,multicentre trial[J]. Crit Care, 2010,14(2):R67. DOI URL PMID
[15]	Bein T, Weber-Carstens S, Apfelbacher C. Long-term outcome after the acute respiratory distress syndrome:different from general critical illness?[J]. Curr Opin Crit Care, 2018,24(1):35-40. DOI URL PMID
	Bein T, Weber-Carstens S, Apfelbacher C. Long-term outcome after the acute respiratory distress syndrome:different from general critical illness?[J]. Curr Opin Crit Care, 2018,24(1):35-40. DOI URL PMID
[16]	Vesz PS, Cremonese RV, Rosa RG, et al. Impact of mechanical ventilation on quality of life and functional status after ICU discharge:a cross-sectional study[J]. Rev Assoc Med Bras, 2018,64(1):47-53. DOI URL PMID
	Vesz PS, Cremonese RV, Rosa RG, et al. Impact of mechanical ventilation on quality of life and functional status after ICU discharge:a cross-sectional study[J]. Rev Assoc Med Bras, 2018,64(1):47-53. DOI URL PMID
[17]	Cabral CDR, Teixeira C, Rosa RG, et al. Mortality,morbidity,and quality-of-life outcomes of patients requiring≥14 days of mechanical ventilation:a 12-monthpost-intensive-care-unit cohort study[J]. Rev Bras Ter Intensiva, 2019,31(3):425-427. DOI URL PMID
	Cabral CDR, Teixeira C, Rosa RG, et al. Mortality,morbidity,and quality-of-life outcomes of patients requiring≥14 days of mechanical ventilation:a 12-monthpost-intensive-care-unit cohort study[J]. Rev Bras Ter Intensiva, 2019,31(3):425-427. DOI URL PMID
[18]	Devlin JW, Skrobik Y, Gélinas C, et al. Clinical practice gui-delines for the prevention and management of pain,agitation/sedation,delirium,immobility,and sleep disruption in adult patients in the ICU[J]. Crit Care Med, 2018,46(9):e825-e873. DOI URL PMID
	Devlin JW, Skrobik Y, Gélinas C, et al. Clinical practice gui-delines for the prevention and management of pain,agitation/sedation,delirium,immobility,and sleep disruption in adult patients in the ICU[J]. Crit Care Med, 2018,46(9):e825-e873. DOI URL PMID
[19]	Nunes SL, Forsberg S, Blomqvist H, et al. Effect of sedation regimen on weaning from mechanical ventilation in the intensive care unit[J]. Clin Drug Investig, 2018,38(6):535-543. DOI URL PMID
	Nunes SL, Forsberg S, Blomqvist H, et al. Effect of sedation regimen on weaning from mechanical ventilation in the intensive care unit[J]. Clin Drug Investig, 2018,38(6):535-543. DOI URL PMID
[20]	Eggmann S, Luder G, Verra ML, et al. Functional ability and quality of life in critical illness survivors with intensive care unit acquired weakness:a secondary analysis of a randomised controlled trial[J]. PLoS One, 2020,15(3):e0229725. DOI URL PMID
	Eggmann S, Luder G, Verra ML, et al. Functional ability and quality of life in critical illness survivors with intensive care unit acquired weakness:a secondary analysis of a randomised controlled trial[J]. PLoS One, 2020,15(3):e0229725. DOI URL PMID
[21]	Kohler J, Borchers F, Endres M, et al. Cognitive deficits follo-wing intensive care[J]. Dtsch Arztebl Int, 2019,116(38):627-634. DOI URL PMID
	Kohler J, Borchers F, Endres M, et al. Cognitive deficits follo-wing intensive care[J]. Dtsch Arztebl Int, 2019,116(38):627-634. DOI URL PMID
[22]	Duggan MC, Wang L, Wilson JE, et al. The relationship between executive dysfunction,depression,and mental health-related quality of life in survivors of critical illness:results from the BRAIN-ICU investigation[J]. J Crit Care, 2017,37:72-79. DOI URL PMID
	Duggan MC, Wang L, Wilson JE, et al. The relationship between executive dysfunction,depression,and mental health-related quality of life in survivors of critical illness:results from the BRAIN-ICU investigation[J]. J Crit Care, 2017,37:72-79. DOI URL PMID
[23]	Hatch R, Young D, Barber VS, et al. Anxiety,depression and post traumatic stress disorder after critical illness:a UK-wide prospective cohort study[J]. Crit Care, 2018,22(1):310. DOI URL PMID
	Hatch R, Young D, Barber VS, et al. Anxiety,depression and post traumatic stress disorder after critical illness:a UK-wide prospective cohort study[J]. Crit Care, 2018,22(1):310. DOI URL PMID
[24]	Wang S, Mosher C, Perkins AJ, et al. Post-intensive care unit psychiatric comorbidity and quality of life[J]. J Hosp Med, 2017,12(10):831-835. DOI URL PMID
	Wang S, Mosher C, Perkins AJ, et al. Post-intensive care unit psychiatric comorbidity and quality of life[J]. J Hosp Med, 2017,12(10):831-835. DOI URL PMID
[25]	Farhan H, Moreno-Duarte I, Latronico N, et al. Acquired muscle weakness in the surgical intensive care unit:nosology,epidemiology,diagnosis,and prevention[J]. Anesthesiol, 2016,124(1):207-234. DOI URL
	Farhan H, Moreno-Duarte I, Latronico N, et al. Acquired muscle weakness in the surgical intensive care unit:nosology,epidemiology,diagnosis,and prevention[J]. Anesthesiol, 2016,124(1):207-234. DOI URL
[26]	韩汝宁, 李秀川, 赵士兵, 等. ICU患者早期康复方案的构建及应用研究[J]. 中华护理杂志, 2020,55(1):8-15.
	韩汝宁, 李秀川, 赵士兵, 等. ICU患者早期康复方案的构建及应用研究[J]. 中华护理杂志, 2020,55(1):8-15.
	Han RN, Li XC, Zhao SB, et al. Construction and practice of early rehabilitation scheme to prevent intensive care unite acquired weakness[J]. Chin J Nurs, 2020,55(1):8-15.
	Han RN, Li XC, Zhao SB, et al. Construction and practice of early rehabilitation scheme to prevent intensive care unite acquired weakness[J]. Chin J Nurs, 2020,55(1):8-15.
[27]	张秀华, 孙桂华. ICU获得性衰弱的危险因素以及对患者近远期预后的影响[J]. 解放军护理杂志, 2018,35(12):39-42.
	张秀华, 孙桂华. ICU获得性衰弱的危险因素以及对患者近远期预后的影响[J]. 解放军护理杂志, 2018,35(12):39-42.
	Zhang XH, Sun GH. Short and long-term effect of ICU-acquired weakness on the prognosis of critically ill patients[J]. Nurs J Chin PL A, 2018,35(12):39-42.
	Zhang XH, Sun GH. Short and long-term effect of ICU-acquired weakness on the prognosis of critically ill patients[J]. Nurs J Chin PL A, 2018,35(12):39-42.
[28]	Sidiras G, Patsaki I, Karatzanos E, et al. Long term follow-up of quality of life and functional ability in patients with ICU acquired weakness-a post hoc analysis[J]. J Crit Care, 2019,53:223-230. URL PMID
	Sidiras G, Patsaki I, Karatzanos E, et al. Long term follow-up of quality of life and functional ability in patients with ICU acquired weakness-a post hoc analysis[J]. J Crit Care, 2019,53:223-230. URL PMID
[29]	Altman MT, Knauert MP, Pisani MA. Sleep disturbance after hospitalization and critical illness:a systematic review[J]. Ann Am Thorac Soc, 2017,14(9):1457-1468. DOI URL PMID
	Altman MT, Knauert MP, Pisani MA. Sleep disturbance after hospitalization and critical illness:a systematic review[J]. Ann Am Thorac Soc, 2017,14(9):1457-1468. DOI URL PMID
[30]	Kemp HI, Laycock H, Costello A, et al. Chronic pain in critical care survivors:a narrative review[J]. Br J Anaesth, 2019,123(2):e372-e384. DOI URL PMID
	Kemp HI, Laycock H, Costello A, et al. Chronic pain in critical care survivors:a narrative review[J]. Br J Anaesth, 2019,123(2):e372-e384. DOI URL PMID
[31]	Baumbach P, Götz T, Günther A, et al. Chronic intensive care-related pain:exploratory analysis on predictors and influence on health-related quality of life[J]. Eur J Pain, 2018,22(2):402-413. DOI URL PMID
	Baumbach P, Götz T, Günther A, et al. Chronic intensive care-related pain:exploratory analysis on predictors and influence on health-related quality of life[J]. Eur J Pain, 2018,22(2):402-413. DOI URL PMID
[32]	Heyland DK, Garland A, Bagshaw SM, et al. Recovery after cri-tical illness in patients aged 80 years or older:a multi-center prospective observational cohort study[J]. Intensive Care Med, 2015,41(11):1911-1920. DOI URL PMID
	Heyland DK, Garland A, Bagshaw SM, et al. Recovery after cri-tical illness in patients aged 80 years or older:a multi-center prospective observational cohort study[J]. Intensive Care Med, 2015,41(11):1911-1920. DOI URL PMID
[33]	Lasocki S, Lefebvre T, Mayeur C, et al. Iron deficiency diagnosed using hepcidin on critical care discharge is an independent risk factor for death and poor quality of life at one year:an observational prospective study on 1161 patients[J]. Crit Care, 2018,22(1):314. DOI URL PMID
	Lasocki S, Lefebvre T, Mayeur C, et al. Iron deficiency diagnosed using hepcidin on critical care discharge is an independent risk factor for death and poor quality of life at one year:an observational prospective study on 1161 patients[J]. Crit Care, 2018,22(1):314. DOI URL PMID
[34]	Kayambu G, Boots R, Paratz J. Early physical rehabilitation in intensive care patients with sepsis syndromes:a pilot randomised controlled trial[J]. Intensive Care Med, 2015,41(5):865-874. DOI URL PMID
	Kayambu G, Boots R, Paratz J. Early physical rehabilitation in intensive care patients with sepsis syndromes:a pilot randomised controlled trial[J]. Intensive Care Med, 2015,41(5):865-874. DOI URL PMID
[35]	Morris PE, Berry MJ, Files DC, et al. Standardized rehabilitation and hospital length of stay among patients with acute respiratory failure:a randomized clinical trial[J]. JAMA, 2016,315(24):2694-2702. DOI URL PMID
	Morris PE, Berry MJ, Files DC, et al. Standardized rehabilitation and hospital length of stay among patients with acute respiratory failure:a randomized clinical trial[J]. JAMA, 2016,315(24):2694-2702. DOI URL PMID
[36]	Hodgson CL, Bailey M, Bellomo R, et al. A binational multicenter pilot feasibility randomized controlled trial of early goal-directed mobilization in the ICU[J]. Crit Care Med, 2016,44(6):1145-1152. DOI URL PMID
	Hodgson CL, Bailey M, Bellomo R, et al. A binational multicenter pilot feasibility randomized controlled trial of early goal-directed mobilization in the ICU[J]. Crit Care Med, 2016,44(6):1145-1152. DOI URL PMID
[37]	Fuke R, Hifumi T, Kondo Y, et al. Early rehabilitation to prevent postintensive care syndrome in patients with critical illness:a systematic review and meta-analysis[J]. BMJ Open, 2018,8(5):e019998. DOI URL PMID
	Fuke R, Hifumi T, Kondo Y, et al. Early rehabilitation to prevent postintensive care syndrome in patients with critical illness:a systematic review and meta-analysis[J]. BMJ Open, 2018,8(5):e019998. DOI URL PMID
[38]	Major ME, Kwakman R, Kho ME, et al. Surviving critical illness:what is next? An expert consensus statement on physical rehabilitation after hospital discharge[J]. Crit Care, 2016,20(1):354. DOI URL PMID
	Major ME, Kwakman R, Kho ME, et al. Surviving critical illness:what is next? An expert consensus statement on physical rehabilitation after hospital discharge[J]. Crit Care, 2016,20(1):354. DOI URL PMID
[39]	Shelly AG, Prabhu NS, Jirange P, et al. Quality of life improves with individualized home-based exercises in critical care survivors[J]. Indian J Crit Care Med, 2017,21(2):89-93. DOI URL PMID
	Shelly AG, Prabhu NS, Jirange P, et al. Quality of life improves with individualized home-based exercises in critical care survivors[J]. Indian J Crit Care Med, 2017,21(2):89-93. DOI URL PMID
[40]	Taito S, Yamauchi K, Tsujimoto Y, et al. Does enhanced physical rehabilitation following intensive care unit discharge improve outcomes in patients who received mechanical ventilation? A systematic review and meta-analysis[J]. BMJ Open, 2019,9(6):e026075. DOI URL PMID
	Taito S, Yamauchi K, Tsujimoto Y, et al. Does enhanced physical rehabilitation following intensive care unit discharge improve outcomes in patients who received mechanical ventilation? A systematic review and meta-analysis[J]. BMJ Open, 2019,9(6):e026075. DOI URL PMID
[41]	申苗苗, 刘华平. 国外ICU日记应用的研究进展[J]. 护理研究, 2019,33(14):2443-2445.
	申苗苗, 刘华平. 国外ICU日记应用的研究进展[J]. 护理研究, 2019,33(14):2443-2445.
	Shen MM, Liu HP. Application status and research progress of ICU diaries abroad[J]. Chin Nurs Res, 2019,33(14):2443-2445.
	Shen MM, Liu HP. Application status and research progress of ICU diaries abroad[J]. Chin Nurs Res, 2019,33(14):2443-2445.
[42]	李真, 吴欣娟, 杨慧, 等. ICU日记对患者及家属心理健康干预效果的Meta分析[J]. 中华护理杂志, 2020,55(7):1091-1096.
	李真, 吴欣娟, 杨慧, 等. ICU日记对患者及家属心理健康干预效果的Meta分析[J]. 中华护理杂志, 2020,55(7):1091-1096.
	Li Z, Wu XJ, Yang H, et al. The effectiveness of ICU diary on mental health status of ICU patients and their family members:a systematic review and meta-analysis[J]. Chin J Nurs, 2020,55(7):1091-1096.
	Li Z, Wu XJ, Yang H, et al. The effectiveness of ICU diary on mental health status of ICU patients and their family members:a systematic review and meta-analysis[J]. Chin J Nurs, 2020,55(7):1091-1096.
[43]	Barreto BB, Luz M, Rios MNO, et al. The impact of intensive care unit diaries on patients’ and relatives’ outcomes:a sys-tematic review and meta-analysis[J]. Crit Care, 2019,23(1):411. DOI URL PMID
	Barreto BB, Luz M, Rios MNO, et al. The impact of intensive care unit diaries on patients’ and relatives’ outcomes:a sys-tematic review and meta-analysis[J]. Crit Care, 2019,23(1):411. DOI URL PMID
[44]	Wang S, Xin HN, Chung Lim Vico C, et al. Effect of an ICU diary on psychiatric disorders,quality of life,and sleep quality among adult cardiac surgical ICU survivors:a randomized controlled trial[J]. Crit Care, 2020,24(1):81. DOI URL PMID
	Wang S, Xin HN, Chung Lim Vico C, et al. Effect of an ICU diary on psychiatric disorders,quality of life,and sleep quality among adult cardiac surgical ICU survivors:a randomized controlled trial[J]. Crit Care, 2020,24(1):81. DOI URL PMID
[45]	Bendavid I, Singer P, Theilla M, et al. Nutrition Day ICU:a 7 year worldwide prevalence study of nutrition practice in intensive care[J]. Clin Nutr, 2017,36(4):1122-1129. DOI URL PMID
	Bendavid I, Singer P, Theilla M, et al. Nutrition Day ICU:a 7 year worldwide prevalence study of nutrition practice in intensive care[J]. Clin Nutr, 2017,36(4):1122-1129. DOI URL PMID
[46]	Singer P. Preserving the quality of life:nutrition in the ICU[J]. Crit Care, 2019,23(Suppl 1):139. DOI URL PMID
	Singer P. Preserving the quality of life:nutrition in the ICU[J]. Crit Care, 2019,23(Suppl 1):139. DOI URL PMID
[47]	Allingstrup MJ, Kondrup J, Wiis J, et al. Early goal-directed nutrition versus standard of care in adult intensive care patients:the single-centre,randomised,outcome assessor blinded EAT-ICU trial[J]. Intensive Care Med, 2017,43(11):1637-1647. DOI URL PMID
	Allingstrup MJ, Kondrup J, Wiis J, et al. Early goal-directed nutrition versus standard of care in adult intensive care patients:the single-centre,randomised,outcome assessor blinded EAT-ICU trial[J]. Intensive Care Med, 2017,43(11):1637-1647. DOI URL PMID
[48]	Heyland DK, Day A, Clarke GJ, et al. Nutrition and Exercise in Critical Illness Trial(NEXIS Trial):a protocol of a multicentred,randomised controlled trial of combined cycle ergometry and amino acid supplementation commenced early during critical illness[J]. BMJ Open, 2019,9(7):e027893. DOI URL PMID
	Heyland DK, Day A, Clarke GJ, et al. Nutrition and Exercise in Critical Illness Trial(NEXIS Trial):a protocol of a multicentred,randomised controlled trial of combined cycle ergometry and amino acid supplementation commenced early during critical illness[J]. BMJ Open, 2019,9(7):e027893. DOI URL PMID
[49]	Schofield-Robinson OJ, Lewis SR, Smith AF, et al. Follow-up services for improving long-term outcomes in intensive care unit(ICU)survivors[J]. Cochrane Database Syst Rev, 2018,11(11):CD012701.
	Schofield-Robinson OJ, Lewis SR, Smith AF, et al. Follow-up services for improving long-term outcomes in intensive care unit(ICU)survivors[J]. Cochrane Database Syst Rev, 2018,11(11):CD012701.