doi:10.3761/j.issn.0254-1769.2020.08.029

Abstract

Key words: Liver Transplantation, Recipients, Frailty, Nursing Assessment, Review

摘要：

肝移植是目前公认的治疗终末期肝病的最有效措施。终末期肝病患者移植前后易出现各种并发症,使其处于不良的躯体功能状态,表现为营养不良、机体运动量减少和活动无耐力,这种功能状态可被描述为衰弱。衰弱是多系统功能衰退累积导致的一种病理生理综合征,该文对肝移植受者衰弱的评估工具、影响因素和干预方法进行综述,以提高医护人员对肝移植受者衰弱的认识,并为后续开展干预工作提供指导。

关键词: 肝移植, 受者, 衰弱, 护理评估, 综述

郭利敏, 孟萌, 关玉珠, 李乐之. 肝移植受者衰弱的研究进展[J]. 中华护理杂志, 2020, 55(8): 1265-1270.

References 46

[1]	陈实. 肝移植现状与面临的挑战[J]. 中国普外基础与临床杂志, 2003,10(4):315-317.
[2]	Lai JC, Sonnenday CJ, Tapper EB, et al. Frailty in liver transplantation:an expert opinion statement from the American society of transplantation liver and intestinal community of practice[J]. Am J Transplant, 2019,19(7):1896-1906. URL PMID
[3]	Fried LP, Tangen CM, Walston J, et al. Frailty in older adults:evidence for a phenotype[J]. J Gerontol A Biol Sci Med Sci, 2001,56(3):M146-M156. URL PMID
[4]	Sinclair M, Poltavskiy E, Dodge JL, et al. Frailty is independently associated with increased hospitalisation days in patients on the liver transplant waitlist[J]. World J Gastroenterol, 2017,23(5):899-905. DOI URL PMID
[5]	Duarte-Rojo A, Ruiz-Margáin A, Montaño-Loza AJ, et al. Exercise and physical activity for patients with end-stage liver disease:improving functional status and sarcopenia while on the transplant waiting list[J]. Liver Transpl, 2018,24(1):122-139.
[6]	Cron DC, Friedman JF, Winder GS, et al. Depression and frailty in patients with end-stage liver disease referred for transplant evaluation[J]. Am J Transplant, 2016,16(6):1805-1811. URL PMID
[7]	Saxton A, Velanovich V. Preoperative frailty and quality of life as predictors of postoperative complications[J]. Ann Surg, 2011,253(6):1223-1229. URL PMID
[8]	Lai JC, Segev DL, McCulloch CE,et al. Physical frailty after liver transplantation[J]. Am J Transplant, 2018,18(8):1986-1994. DOI URL PMID
[9]	McAdams-DeMarco MA, King EA, Luo X, et al. Frailty,length of stay,and mortality in kidney transplant recipients:a national registry and prospective cohort study[J]. Ann Surg, 2017,266(6):1084-1090. DOI URL PMID
[10]	Garonzik-Wang JM, Govindan P, Grinnan JW, et al. Frailty and delayed graft function in kidney transplant recipients[J]. Arch Surg, 2012,147(2):190-193. URL PMID
[11]	Malinis MF, Chen S, Allore HG, et al. Outcomes among older adult liver transplantation recipients in the model of end stage liver disease(MELD) era[J]. Ann Transplant, 2014,19:478-487. URL PMID
[12]	Tandon P, Reddy KR, O’Leary JG, et al. A Karnofsky performance status-based score predicts death after hospital discharge in patients with cirrhosis[J]. Hepatology, 2017,65(1):217-224. URL PMID
[13]	Tapper EB, Finkelstein D, Mittleman MA, et al. Standard assessments of frailty are validated predictors of mortality in hospitalized patients with cirrhosis[J]. Hepatology, 2015,62(2):584-590. URL PMID
[14]	Tandon P, Tangri N, Thomas L, et al. A rapid bedside screen to predict unplanned hospitalization and death in outpatients with cirrhosis:a prospective evaluation of the clinical frailty scale[J]. Am J Gastroenterol, 2016,111(12):1759-1767. URL PMID
[15]	Samoylova ML, Covinsky KE, Haftek M, et al. Disability in patients with end-stage liver disease:results from the functional assessment in liver transplantation study[J]. Liver Tra-nspl, 2017,23(3):292-298.
[16]	Rockwood K, Song XW, MacKnight C, et al. A global clinical measure of fitness and frailty in elderly people[J]. CMAJ, 2005,173(5):489-495. URL PMID
[17]	Ney M, Tangri N, Dobbs B, et al. Predicting hepatic encepha-lopathy-related hospitalizations using a composite assessment of cognitive impairment and frailty in 355 patients with cirrhosis[J]. Am J Gastroenterol, 2018,113(10):1506-1515. URL PMID
[18]	Lai JC, Covinsky KE, Dodge JL, et al. Development of a novel frailty index to predict mortality in patients with end-stage liver disease[J]. Hepatology, 2017,66(2):564-574. DOI URL PMID
[19]	Lai JC, Covinsky KE, McCulloch CE, et al. The liver frailty index improves mortality prediction of the subjective clinician assessment in patients with cirrhosis[J]. Am J Gastroenterol, 2018,113(2):235-242. URL PMID
[20]	Guaraldi G, Dolci G, Zona S, et al. A frailty index predicts post-liver transplant morbidity and mortality in HIV-positive patients[J]. AIDS Res Ther, 2017,14(1):37. DOI URL PMID
[21]	Westbury LD, Fuggle NR, Syddall HE, et al. Relationships between markers of inflammation and muscle mass,strength and function:findings from the Hertfordshire Cohort Study[J]. Cal-cif Tissue Int, 2018,102(3):287-295.
[22]	Buganza-Torio E, Mitchell N, Abraldes JG, et al. Depression in cirrhosis-a prospective evaluation of the prevalence,predictors and development of a screening nomogram[J]. Aliment Pharmacol Ther, 2019,49(2):194-201. URL PMID
[23]	周巧学, 周建荣, 库敏, 等. 社区高龄老年人衰弱状况及影响因素的研究[J]. 护理学杂志, 2019,34(21):68-72.
[24]	Smit E, Winters-Stone KM, Loprinzi PD, et al. Lower nutritional status and higher food insufficiency in frail older US adults[J]. Br J Nutr, 2013,110(1):172-178. URL PMID
[25]	侯晓琳, 高静, 吴晨曦, 等. 养老机构老年人衰弱现状及分析[J]. 中华护理杂志, 2018,53(1):88-93.
[26]	张可可, 朱鸣雷, 刘晓红, 等. 北京部分社区老年人共病及老年综合征调查分析[J]. 中国实用内科杂志, 2016,36(5):419-421.
[27]	Bhanji RA, Narayanan P, Moynagh MR, et al. Differing impact of sarcopenia and frailty in nonalcoholic steatohepatitis and alcoholic liver disease[J]. Liver Transpl, 2019,25(1):14-24. URL PMID
[28]	Lai JC, Volk ML, Strasburg D, et al. Performance-based measures associate with frailty in patients with end-stage liver disease[J]. Transplantation, 2016,100(12):2656-2660. URL PMID
[29]	陈潇, 张玉侠, 俞静娴, 等. 肝移植受者症状群及其影响因素的研究[J]. 中华护理杂志, 2019,54(8):1130-1135.
[30]	Natasha HD, Paulo N A, Babak M, et al. Functional status predicts postoperative mortality after liver transplantation[J]. Clinical Transplantation, 2016,30(11):1403-1410. DOI URL
[31]	方幸, 徐建鸣. 老年心脏手术患者衰弱评估及安全管理研究进展[J]. 中华护理杂志, 2019,54(2):206-210.
[32]	王守琦, 石颖, 张美玲, 等. 老年人衰弱干预的研究进展[J]. 中华护理杂志, 2017,52(3):365-368.
[33]	Dasarathy S, Merli M. Sarcopenia from mechanism to diagnosis and treatment in liver disease[J]. J Hepatol, 2016,65(6):1232-1244.
[34]	Morkane CM, Kearney O, Bruce DA, et al. An outpatient hospital-based exercise training program for patients with cirrhotic liver disease awaiting transplantation:a feasibility trial[J]. Transplantation, 2020,104(1):97-103. URL PMID
[35]	Williams FR, Vallance A, Faulkner T, et al. Home-based exercise in patients awaiting liver transplantation:a feasibility study[J]. Liver Transpl, 2019,25(7):995-1006. DOI URL PMID
[36]	张荣利, 揭彬. 早期活动干预对肝移植患者术后康复的影响[J]. 中华护理杂志, 2006,41(5):391-394.
[37]	Barillaro C, Liperoti R, Martone AM, et al. The new metabolic treatments for sarcopenia[J]. Aging Clin Exp Res, 2013,25(2):119-127. DOI URL
[38]	郭会敏, 徐曼曼, 孔明, 等. 个体化营养干预对有营养风险的慢加急性肝衰竭患者预后的影响[J]. 北京医学, 2019,41(10):957-959,962.
[39]	沈秋月, 岑爱萍, 李国宏, 等. 肝功能衰竭患者营养干预的方法及效果[J]. 解放军护理杂志, 2015,32(23):41-44,72.
[40]	Lim DS. Prehabilitation:is it worth our while[J]. Am J Phys Med Rehabil, 2015,94(8):e74. DOI URL PMID
[41]	Gillis C, Li C, Lee L, et al. Prehabilitation versus rehabilitation:a randomized control trial in patients undergoing colorectal resection for cancer[J]. Anesthesiology, 2014,121(5):937-947.
[42]	Williams AM, Waits S, Englesbe MJ. The importance of prehabilitation in liver transplantation[J]. Curr Transpl Rep, 2015,2(4):312-315.
[43]	Kruger C, McNeely ML, Bailey RJ, et al. Home exercise training improves exercise capacity in cirrhosis patients:role of exercise adherence[J]. Sci Rep, 2018,8(1):99.
[44]	Carli F, Scheede-Bergdahl C. Prehabilitation to enhance perioperative care[J]. Anesthesiol Clin, 2015,33(1):17-33.
[45]	Ng TP, Feng L, Nyunt MS, et al. Nutritional,physical,cognitive and combination interventions and frailty reversal among older adults:a randomized controlled trial[J]. Am J Med, 2015,128(11):1225-1236.
[46]	曹晓东, 黄云娟, 朱亭立, 等. 认知行为干预对行肺移植患者等待肺移植期间心理状态的影响[J]. 中华护理杂志, 2013,48(5):455-458.

肝移植受者衰弱的研究进展

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