Abstract: Objective To retrieve,evaluate and integrate best practice evidence for targeted temperature management after cardiac arrest. Methods According to the “6S” evidence model,UpToDate,Joanna Briggs Institute（JBI）,National Guideline Clearinghouse（NGC）,National Institute for Health and Care Excellence（NICE）,Scottish Intercollegiate Guidelines Network（SIGN）,New Zealand Guidelines Group（NZGG）,Queensland Clinical Guidelines（QCG）,Australian Government National Health and Medical Research Council（NHMRC）,Guidelines International Network（GIN）,Registered Nurses' Association of Ontario（RNAO）,the Chinese Cochrane Center,medlive.cn,American Heart Association（AHA）,European Society of Cardiology（ESC）,European Resuscitation Council（ERC）,International Liaison Committee on Resuscitation（ILCOR）,Australian Resuscitation Council（ARC）,PubMed,Chinese Biology Medical literature database（CBM） and Wanfang Med Online were searched. The evidences were about targeted temperature management for adult patients who recover spontaneous circulation from cardiac arrest but are still comatose,including clinical decision,guidelines,evidence summary and expert consensus. Two researchers evaluated the quality of the included literature,as well as extracted and summarized the evidence that met the quality criteria. Results A total of 11 articles were included,including 1 clinical decision,6 guidelines,1 evidence summary,3 expert consensuses. Finally,24 pieces of best evidences were summarized. Conclusion This study summarizes the best evidence on targeted temperature management after cardiac arrest,which can provide evidence-based supports for medical staffs.

Key words: Cardiac Arrest, Cardiopulmonary Resuscitation, Targeted Temperature Management, Mild Hypothermia, Therapeutic Hypothermia, Evidence-based Nursing, Emergency

摘要： 目的 检索、评价和整合心搏骤停后目标体温管理的最佳实践证据。 方法 按照“6S”证据模型,计算机检索UpToDate、循证卫生保健中心数据库、美国指南网、英国国家临床医学研究所指南网、苏格兰院际间指南网、新西兰指南组网站、昆士兰临床指南网、澳大利亚国家卫生医学研究理事会、国际网络指南网、加拿大安大略省注册护士协会网站、中国循证医学中心网站、中国医脉通指南网、美国心脏协会网站、欧洲心脏病学会、欧洲复苏委员会网站、国际复苏联络委员会网站、澳大利亚复苏委员会网站、PubMed、中国生物医学文献数据库、万方医学网关于心搏骤停后自主循环恢复但仍昏迷的成人患者目标体温管理的证据,包括临床决策、指南、证据总结、专家共识。由2名研究者对纳入的文献质量进行评价,并对符合质量标准的文献进行证据提取和汇总。 结果 共纳入文献11篇,包括临床决策1篇、指南6篇、证据总结1篇、专家共识3篇,最终总结了24条最佳证据。 结论 总结的目前关于心搏骤停后目标体温管理的最佳证据可为医护人员提供循证依据。

关键词: 心搏骤停, 心肺复苏, 目标体温管理, 亚低温, 治疗性低体温, 循证护理, 急诊